Opinion statement
Anaemia is a common multifactorial extraintestinal manifestation in IBD patients. Moreover, anaemia represents an important health problem among the elderly population and has a significant impact on healthcare utilisation and costs. Data on the prevalence, diagnosis and management of anaemia in elderly IBD patients are scarce, since clinical trials have largely excluded this population. In this review, we reconsider anaemia in older IBD patients in the light of new diagnostic and therapeutic tools.
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Abbreviations
- ACD:
-
Anaemia of chronic disease
- CD:
-
Crohn’s disease
- CHr:
-
Reticulocyte haemoglobin content
- ESA:
-
Erythropoiesis-stimulating agent
- Hb:
-
Haemoglobin
- %HYPO:
-
Hypochromic red cells
- IBD:
-
Inflammatory bowel disease
- ID:
-
Iron deficiency
- IDA:
-
Iron deficiency anaemia
- RES:
-
Reticuloendothelial system
- sTfR:
-
Soluble transferrin receptors
- TfS:
-
Transferrin saturation
- TIBC:
-
Total iron binding capacity
- UC:
-
Ulcerative colitis
- ZPP:
-
Zinc protoporphyrin
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Conflict of Interest
Jürgen Stein has received consultancy fees from Abbvie, Fresenius-Kabi, Immundiagnostik, MSD, Pharmacosmos, Takeda, and Vifor. Dr. Stein has also received payment for lectures from Abbvie, Falk Foundation, Ferring, Immundiagnostik, MSD, Pharmacosmos, Takeda, Thermofischer and Vifor. Additionally, Dr. Stein has received payment for manuscript preparation from Abbvie, Falk Foundation and MSD.
Axel U. Dignass has received consultancy fees from Abbott, MSD, Ferring, UCB, Otsuka, Roche/Genentech, Takeda, Pharmacosmos, Holystone Biotech and Falk Foundation. Dr. Dignass has also received grants from Institut für Gemeinwohl and Stiftung Leben mit Krebs as well as payment for lectures including service on speakers bureaus from Falk Foundation, Ferring, MSD, Abbott, Otsuka, Vifor, Stiftung Leben mit Krebs, Kompetenznetz CED, Takeda and Pharmacosmos. Additionally, Dr. Dignass has received payment for manuscript preparation from Falk Foundation and payment for development of education presentations from Abbott, Pharmacosmos, Falk Foundation and Ferring.
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Stein, J., Dignass, A.U. Anaemia in the Elderly IBD Patient. Curr Treat Options Gastro 13, 308–318 (2015). https://doi.org/10.1007/s11938-015-0062-y
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DOI: https://doi.org/10.1007/s11938-015-0062-y