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Dietary Renaissance in IBS: Has Food Replaced Medications as a Primary Treatment Strategy?

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Opinion Statement

The medical community has only recently started to focus attention on the role of food in the pathogenesis of irritable bowel syndrome (IBS), though the association between food and gastrointestinal (GI) symptoms has been recognized by patients for decades. Health care providers receive little formal training in the dietary management of IBS and have traditionally viewed dietary interventions with skepticism. There is mounting evidence that links food to changes in motility, visceral sensation, microbiome, permeability, immune activation, and brain–gut interactions—all key elements in the pathogenesis of IBS. The role of specific dietary modification in the management of IBS has not been rigorously investigated until recently. There is now credible evidence suggesting that targeted dietary carbohydrate exclusion provides clinical benefits to IBS patients. There is emerging evidence to suggest that proteins such as gluten, as well as food chemicals, may play a role in IBS.

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Conflict of Interest

Marisa Spencer and Shanti Eswaran declare that they have no conflict of interest.

William D. Chey has received consultancy fees from Astra-Zeneca, Forest, Ironwood, Perrigo, Prometheus, Nestle, Sucampo, Takeda, Furiex, SK, Ferring, and Entera. He also has received grants from Ironwood, Prometheus, Nestle, and Perrigo.

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  1. Division of Gastroenterology, University of Michigan Health System, 3912 Taubman Center, SPC 5362, Ann Arbor, MI, 48109-5362, USA

    Marisa Spencer MD, William D. Chey MD & Shanti Eswaran MD

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  1. Marisa Spencer MD
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  2. William D. Chey MD
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Correspondence to Shanti Eswaran MD.

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Spencer, M., Chey, W.D. & Eswaran, S. Dietary Renaissance in IBS: Has Food Replaced Medications as a Primary Treatment Strategy?. Curr Treat Options Gastro 12, 424–440 (2014). https://doi.org/10.1007/s11938-014-0031-x

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