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Current insights in Whipple’s disease

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Opinion statement

Therapy for Whipple’s disease should be continued for a minimum of 1 year, and the regimen should include an agent or agents that achieve acceptable concentrations in the central nervous system, given the likelihood of recurrence at this site. Clinical follow-up of proven cases of Whipple’s disease should be conducted for a minimum of 10 years after discontinuation of therapy, given the potential for late relapses. Polymerase chain reaction analysis is preferred rather than endoscopy when evaluating for disease recurrence.

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Authors and Affiliations

  1. Department of Internal Medicine, Eastern Virginia Medical School, Hofheimer Hall, 825 Fairfax Avenue, 23507-1912, Norfolk, VA, USA

    Mark C. Flemmer MD & Ronald W. Flenner MD

Authors
  1. Mark C. Flemmer MD
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  2. Ronald W. Flenner MD
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Flemmer, M.C., Flenner, R.W. Current insights in Whipple’s disease. Curr Treat Options Gastro 6, 13–16 (2003). https://doi.org/10.1007/s11938-003-0028-3

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  • DOI: https://doi.org/10.1007/s11938-003-0028-3

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