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Post-myocardial infarction pericarditis

Opinion statement

Post-myocardial infarction pericarditis occurs in approximately 5% to 6% of patients who receive thrombolytic agents. It should be suspected in any patient with pleuropericardial pain. A pericardial friction rub may or may not be present. Differentiation of pericarditis from recurrent angina may be difficult, but a careful history and evaluation of serial electrocardiograms can help distinguish the two entities. Dressler’s syndrome, pericarditis that occurs at least 1 week following myocardial infarction, is now exceedingly rare. Most cases of pericarditis have a benign course; however, because pericarditis is associ-ated with larger infarcts, overall long-term mortality rate is increased. Rare complications include hemopericardium, cardiac tamponade, and constrictive pericarditis. Therapy is directed toward relief of pain, which usually responds well to nonsteroidal anti-inflammatory agents (eg, aspirin or ibuprofen).

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References and Recommended Reading

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Indik, J.H., Alpert, J.S. Post-myocardial infarction pericarditis. Curr Treat Options Cardio Med 2, 351–355 (2000).

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  • Indomethacin
  • Ibuprofen
  • Pericardial Effusion
  • Pericarditis
  • Main Side Effect