Skip to main content

Advertisement

SpringerLink
Log in

Exercise and Cardio-Oncology Rehab

  • Cardio-oncology (M Fradley, Section Editor)
  • Published:
Current Treatment Options in Cardiovascular Medicine Aims and scope Submit manuscript

Abstract

Purpose of Review

To evaluate the evidence supporting the use of exercise training as a treatment strategy to reduce risk of cardiovascular disease (CVD) in cancer populations and to provide an overview of the use of cardiac rehabilitation (CR) in cancer patients and survivors.

Recent Findings

A recent scoping review suggests that CR-style interventions are feasible in cancer patients, but more evidence is needed to establish the benefits of this approach.

Summary

Cancer survivors are at increased risk of CVD as a result of side effects of cancer treatment, shared risk factors for cancer and CVD, and effects from the cancer itself. Aerobic exercise training improves peak VO2, but few models exist to support widespread incorporation of exercise training into cancer care. CR could provide infrastructure to support the incorporation of exercise in cancer populations, but data are limited regarding the feasibility or benefits of CR in cancer patients.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

Papers of particular interest, published recently, have been highlighted as: • Of importance

  1. Miller KD, Siegel RL, Lin CC, Mariotto AB, Kramer JL, Rowland JH, et al. Cancer treatment and survivorship statistics, 2016. CA Cancer J Clin. 2016;66(4):271–89.

    Article  PubMed  Google Scholar 

  2. Caspersen CJ, Powell KE, Christenson GM. Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research. Public Health Rep Wash DC 1974. 1985 Apr;100(2):126–31.

  3. Scott JM, Nilsen TS, Gupta D, Jones LW. Exercise therapy and cardiovascular toxicity in cancer. Circulation. 2018;137(11):1176–91.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Gilchrist SC, Barac A, Ades PA, Alfano CM, Franklin BA, Jones LW, et al. Cardio-oncology rehabilitation to manage cardiovascular outcomes in cancer patients and survivors: a scientific statement from the American Heart Association. Circulation [Internet]. 2019 May 21 [cited 2021 Sep 19];139(21). Available from: https://www.ahajournals.org/doi/10.1161/CIR.0000000000000679.

  5. • Campbell KL, Winters-Stone KM, Wiskemann J, May AM, Schwartz AL, Courneya KS, et al. Exercise guidelines for cancer survivors: consensus statement from International Multidisciplinary Roundtable. Med Sci Sports Exerc. 2019 Nov;51(11):2375–90. This consensus statement from the American College of Sports Medicine provides recommendations for the prescription of exercise to reduce common side effects of cancer treatment.

  6. Chang H-M, Moudgil R, Scarabelli T, Okwuosa TM, Yeh ETH. Cardiovascular complications of cancer therapy: best practices in diagnosis, prevention, and management: part 1. J Am Coll Cardiol. 2017 Nov 14;70(20):2536–51.

  7. Chang H-M, Okwuosa TM, Scarabelli T, Moudgil R, Yeh ETH. Cardiovascular complications of cancer therapy: best practices in diagnosis, prevention, and management: part 2. J Am Coll Cardiol. 2017;70(20):2552–65.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Jones LW, Courneya KS, Mackey JR, Muss HB, Pituskin EN, Scott JM, et al. Cardiopulmonary function and age-related decline across the breast cancer survivorship continuum. J Clin Oncol. 2012;30(20):2530–7.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Alexandre J, Cautela J, Ederhy S, Damaj GL, Salem J-E, Barlesi F, et al. Cardiovascular toxicity related to cancer treatment: a pragmatic approach to the American and European cardio-oncology guidelines. J Am Heart Assoc. 2020;9(18): e018403.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Lenneman CG, Sawyer DB. Cardio-oncology: an update on cardiotoxicity of cancer-related treatment. Circ Res. 2016;118(6):1008–20.

    Article  CAS  PubMed  Google Scholar 

  11. Herrmann J. Adverse cardiac effects of cancer therapies: cardiotoxicity and arrhythmia. Nat Rev Cardiol. 2020;17(8):474–502.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Yu AF, Flynn JR, Moskowitz CS, Scott JM, Oeffinger KC, Dang CT, et al. Long-term cardiopulmonary consequences of treatment-induced cardiotoxicity in survivors of ERBB2-positive breast cancer. JAMA Cardiol. 2020;5(3):309–17.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Hooning MJ, Botma A, Aleman BMP, Baaijens MHA, Bartelink H, Klijn JGM, et al. Long-term risk of cardiovascular disease in 10-year survivors of breast cancer. J Natl Cancer Inst. 2007;99(5):365–75.

    Article  PubMed  Google Scholar 

  14. Chow EJ, Mueller BA, Baker KS, Cushing-Haugen KL, Flowers MED, Martin PJ, et al. Cardiovascular hospitalizations and mortality among recipients of hematopoietic stem cell transplantation. Ann Intern Med. 2011;155(1):21–32.

    Article  PubMed  Google Scholar 

  15. Jones LW, Courneya KS, Mackey JR, Muss HB, Pituskin EN, Scott JM, et al. Cardiopulmonary function and age-related decline across the breast cancer survivorship continuum. J Clin Oncol. 2012;30(20):2530–7.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Hurria A, Jones L, Muss HB. Cancer treatment as an accelerated aging process: assessment, biomarkers, and interventions. Am Soc Clin Oncol Educ Book Am Soc Clin Oncol Annu Meet. 2016;35:e516-522.

    Article  Google Scholar 

  17. • Scott JM, Zabor EC, Schwitzer E, Koelwyn GJ, Adams SC, Nilsen TS, et al. Efficacy of exercise therapy on cardiorespiratory fitness in patients with cancer: a systematic review and meta-analysis. J Clin Oncol. 2018 Aug 1;36(22):2297–305. This systematic review summarizes data from randomized trials showing that exercise interventions improve cardiorespiratory fitness in cancer patients during and after treatment.

  18. Mehta LS, Watson KE, Barac A, Beckie TM, Bittner V, Cruz-Flores S, et al. Cardiovascular disease and breast cancer: where these entities intersect: a scientific statement from the American Heart Association. Circulation. 2018 Feb 20;137(8):e30–66.

  19. Schmid D, Leitzmann MF. Cardiorespiratory fitness as predictor of cancer mortality: a systematic review and meta-analysis. Ann Oncol Off J Eur Soc Med Oncol. 2015;26(2):272–8.

    Article  CAS  Google Scholar 

  20. Moore SC, Lee I-M, Weiderpass E, Campbell PT, Sampson JN, Kitahara CM, et al. Association of leisure-time physical activity with risk of 26 types of cancer in 1.44 million adults. JAMA Intern Med. 2016 Jun 1;176(6):816–25.

  21. • Mctiernan A, Friedenreich CM, Katzmarzyk PT, Powell KE, Macko R, Buchner D, et al. Physical activity in cancer prevention and survival: a systematic review. Med Sci Sports Exerc. 2019 Jun;51(6):1252–61. This systematic review summarizes the observational evidence showing an association between higher levels of physical activity and lower risk of developing and dying from cancer.

  22. Friedenreich CM, Stone CR, Cheung WY, Hayes SC. Physical activity and mortality in cancer survivors: a systematic review and meta-analysis. JNCI Cancer Spectr. 2020 Feb;4(1):pkz080.

  23. Patel AV, Friedenreich CM, Moore SC, Hayes SC, Silver JK, Campbell KL, et al. American College of Sports Medicine roundtable report on physical activity, sedentary behavior, and cancer prevention and control. Med Sci Sports Exerc. 2019;51(11):2391–402.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Chipperfield K, Brooker J, Fletcher J, Burney S. The impact of physical activity on psychosocial outcomes in men receiving androgen deprivation therapy for prostate cancer: a systematic review. Health Psychol Off J Div Health Psychol Am Psychol Assoc. 2014;33(11):1288–97.

    Google Scholar 

  25. van Vulpen JK, Peeters PHM, Velthuis MJ, van der Wall E, May AM. Effects of physical exercise during adjuvant breast cancer treatment on physical and psychosocial dimensions of cancer-related fatigue: a meta-analysis. Maturitas. 2016;85:104–11.

    Article  PubMed  Google Scholar 

  26. Galvão DA, Newton RU, Chambers SK, Spry N, Joseph D, Gardiner RA, et al. Psychological distress in men with prostate cancer undertaking androgen deprivation therapy: modifying effects of exercise from a year-long randomized controlled trial. Prostate Cancer Prostatic Dis. 2021;24(3):758–66.

    Article  PubMed  PubMed Central  Google Scholar 

  27. Singh F, Newton RU, Galvão DA, Spry N, Baker MK. A systematic review of pre-surgical exercise intervention studies with cancer patients. Surg Oncol. 2013;22(2):92–104.

    Article  PubMed  Google Scholar 

  28. Cheema B, Gaul CA, Lane K, Fiatarone Singh MA. Progressive resistance training in breast cancer: a systematic review of clinical trials. Breast Cancer Res Treat. 2008;109(1):9–26.

    Article  PubMed  Google Scholar 

  29. Mustian KM, Alfano CM, Heckler C, Kleckner AS, Kleckner IR, Leach CR, et al. Comparison of pharmaceutical, psychological, and exercise treatments for cancer-related fatigue: a meta-analysis. JAMA Oncol. 2017;3(7):961–8.

    Article  PubMed  PubMed Central  Google Scholar 

  30. Sweegers MG, Altenburg TM, Chinapaw MJ, Kalter J, Verdonck-de Leeuw IM, Courneya KS, et al. Which exercise prescriptions improve quality of life and physical function in patients with cancer during and following treatment? A systematic review and meta-analysis of randomised controlled trials. Br J Sports Med. 2018;52(8):505–13.

    Article  PubMed  Google Scholar 

  31. Lund CM, Dolin TG, Mikkelsen MK, Juhl CB, Vinther A, Nielsen DL. Effect of exercise on physical function and psychological well-being in older patients with colorectal cancer receiving chemotherapy-a systematic review. Clin Colorectal Cancer. 2020;19(4):e243–57.

    Article  PubMed  Google Scholar 

  32. Courneya KS, Vardy JL, O’Callaghan CJ, Friedenreich CM, Campbell KL, Prapavessis H, et al. Effects of a structured exercise program on physical activity and fitness in colon cancer survivors: one year feasibility results from the CHALLENGE trial. Cancer Epidemiol Biomark Prev Publ Am Assoc Cancer Res Cosponsored Am Soc Prev Oncol. 2016;25(6):969–77.

    Article  Google Scholar 

  33. Newton RU, Kenfield SA, Hart NH, Chan JM, Courneya KS, Catto J, et al. Intense exercise for survival among men with metastatic castrate-resistant prostate cancer (INTERVAL-GAP4): a multicentre, randomised, controlled phase III study protocol. BMJ Open. 2018;8(5): e022899.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Rack B, Andergassen U, Neugebauer J, Salmen J, Hepp P, Sommer H, et al. The German SUCCESS C study-the first European lifestyle study on breast cancer. Breast Care Basel Switz. 2010;5(6):395–400.

    Google Scholar 

  35. Villarini A, Pasanisi P, Traina A, Mano MP, Bonanni B, Panico S, et al. Lifestyle and breast cancer recurrences: the DIANA-5 trial. Tumori. 2012;98(1):1–18.

    Article  CAS  PubMed  Google Scholar 

  36. Ligibel JA, Barry WT, Alfano CM, Hershman DL, Irwin ML, Neuhouser M, et al. The breast cancer weight loss (BWEL) trial: randomized phase III trial evaluating the role of weight loss in adjuvant treatment of overweight and obese women with early-stage breast cancer (Alliance A011401). J Clin Oncol. 2018 May 20;36(15_suppl):TPS598–TPS598.

  37. Thomson CA, Crane TE, Miller A, Garcia DO, Basen-Engquist K, Alberts DS. A randomized trial of diet and physical activity in women treated for stage II-IV ovarian cancer: rationale and design of the lifestyle intervention for ovarian cancer enhanced survival (LIVES): an NRG Oncology/Gynecologic Oncology Group (GOG-225) Study. Contemp Clin Trials. 2016;49:181–9.

    Article  PubMed  PubMed Central  Google Scholar 

  38. Bjørke ACH, Sweegers MG, Buffart LM, Raastad T, Nygren P, Berntsen S. Which exercise prescriptions optimize V̇O2 max during cancer treatment? A systematic review and meta-analysis. Scand J Med Sci Sports. 2019;29(9):1274–87.

    Article  PubMed  Google Scholar 

  39. Maginador G, Lixandrão ME, Bortolozo HI, Vechin FC, Sarian LO, Derchain S, et al. Aerobic exercise-induced changes in cardiorespiratory fitness in breast cancer patients receiving chemotherapy: a systematic review and meta-analysis. Cancers. 2020;12(8):E2240.

    Article  PubMed  Google Scholar 

  40. Singh B, Spence RR, Steele ML, Sandler CX, Peake JM, Hayes SC. A systematic review and meta-analysis of the safety, feasibility, and effect of exercise in women with stage II+ breast cancer. Arch Phys Med Rehabil. 2018;99(12):2621–36.

    Article  PubMed  Google Scholar 

  41. Hornsby WE, Douglas PS, West MJ, Kenjale AA, Lane AR, Schwitzer ER, et al. Safety and efficacy of aerobic training in operable breast cancer patients receiving neoadjuvant chemotherapy: a phase II randomized trial. Acta Oncol Stockh Swed. 2014;53(1):65–74.

    Article  Google Scholar 

  42. Wang F, Chandra J, Kleinerman ES. Exercise intervention decreases acute and late doxorubicin-induced cardiotoxicity. Cancer Med. 2021;10(21):7572–84.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  43. Sturgeon K, Schadler K, Muthukumaran G, Ding D, Bajulaiye A, Thomas NJ, et al. Concomitant low-dose doxorubicin treatment and exercise. Am J Physiol Regul Integr Comp Physiol. 2014;307(6):R685-692.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  44. Ansund J, Mijwel S, Bolam KA, Altena R, Wengström Y, Rullman E, et al. High intensity exercise during breast cancer chemotherapy - effects on long-term myocardial damage and physical capacity - data from the OptiTrain RCT. Cardio-Oncol Lond Engl. 2021;7(1):7.

    Article  Google Scholar 

  45. Kirkham AA, Eves ND, Shave RE, Bland KA, Bovard J, Gelmon KA, et al. The effect of an aerobic exercise bout 24 h prior to each doxorubicin treatment for breast cancer on markers of cardiotoxicity and treatment symptoms: a RCT. Breast Cancer Res Treat. 2018;167(3):719–29.

    Article  CAS  PubMed  Google Scholar 

  46. Kirkham AA, Paterson DI, Prado CM, Mackey JR, Courneya KS, Pituskin E, et al. Rationale and design of the caloric restriction and exercise protection from anthracycline toxic effects (CREATE) study: a 3-arm parallel group phase II randomized controlled trial in early breast cancer. BMC Cancer. 2018;18(1):864.

    Article  PubMed  PubMed Central  Google Scholar 

  47. Postigo-Martin P, Peñafiel-Burkhardt R, Gallart-Aragón T, Alcaide-Lucena M, Artacho-Cordón F, Galiano-Castillo N, et al. Attenuating treatment-related cardiotoxicity in women recently diagnosed with breast cancer via a tailored therapeutic exercise program: protocol of the ATOPE trial. Phys Ther. 2021 Mar 3;101(3):pzab014.

  48. Balady GJ, Williams MA, Ades PA, Bittner V, Comoss P, Foody JM, et al. Core components of cardiac rehabilitation/secondary prevention programs: 2007 update: a scientific statement from the American Heart Association Exercise, Cardiac Rehabilitation, and Prevention Committee, the Council on Clinical Cardiology; the Councils on Cardiovascular Nursing, Epidemiology and Prevention, and Nutrition, Physical Activity, and Metabolism; and the American Association of Cardiovascular and Pulmonary Rehabilitation. Circulation. 2007;115(20):2675–82.

    Article  PubMed  Google Scholar 

  49. Ades PA, Keteyian SJ, Wright JS, Hamm LF, Lui K, Newlin K, et al. Increasing cardiac rehabilitation participation from 20% to 70%: a road map from the million hearts cardiac rehabilitation collaborative. Mayo Clin Proc. 2017;92(2):234–42.

    Article  PubMed  Google Scholar 

  50. Smith SC, Benjamin EJ, Bonow RO, Braun LT, Creager MA, Franklin BA, et al. AHA/ACCF secondary prevention and risk reduction therapy for patients with coronary and other atherosclerotic vascular disease: 2011 update: a guideline from the American Heart Association and American College of Cardiology Foundation. Circulation. 2011;124(22):2458–73.

    Article  PubMed  Google Scholar 

  51. Thomas RJ, Beatty AL, Beckie TM, Brewer LC, Brown TM, Forman DE, et al. Home-based cardiac rehabilitation: a scientific statement from the American Association of Cardiovascular and Pulmonary Rehabilitation, the American Heart Association, and the American College of Cardiology. J Am Coll Cardiol. 2019;74(1):133–53.

    Article  PubMed  PubMed Central  Google Scholar 

  52. Anderson L, Oldridge N, Thompson DR, Zwisler A-D, Rees K, Martin N, et al. Exercise-based cardiac rehabilitation for coronary heart disease: Cochrane systematic review and meta-analysis. J Am Coll Cardiol. 2016;67(1):1–12.

    Article  PubMed  Google Scholar 

  53. Powell R, McGregor G, Ennis S, Kimani PK, Underwood M. Is exercise-based cardiac rehabilitation effective? A systematic review and meta-analysis to re-examine the evidence. BMJ Open. 2018;8(3): e019656.

    Article  PubMed  PubMed Central  Google Scholar 

  54. Long L, Anderson L, Dewhirst AM, He J, Bridges C, Gandhi M, et al. Exercise-based cardiac rehabilitation for adults with stable angina. Cochrane Database Syst Rev. 2018 Feb 2;2:CD012786.

  55. Lavie CJ, Milani RV. Cardiac rehabilitation and exercise training in secondary coronary heart disease prevention. Prog Cardiovasc Dis. 2011;53(6):397–403.

    Article  PubMed  Google Scholar 

  56. Long L, Mordi IR, Bridges C, Sagar VA, Davies EJ, Coats AJ, et al. Exercise-based cardiac rehabilitation for adults with heart failure. Cochrane Database Syst Rev. 2019 Jan 29;1:CD003331.

  57. Anderson L, Thompson DR, Oldridge N, Zwisler A-D, Rees K, Martin N, et al. Exercise-based cardiac rehabilitation for coronary heart disease. Cochrane Database Syst Rev. 2016 Jan 5;(1):CD001800.

  58. Ji H, Fang L, Yuan L, Zhang Q. Effects of exercise-based cardiac rehabilitation in patients with acute coronary syndrome: a meta-analysis. Med Sci Monit Int Med J Exp Clin Res. 2019;7(25):5015–27.

    Google Scholar 

  59. Jones LW, Courneya KS, Mackey JR, Muss HB, Pituskin EN, Scott JM, et al. Cardiopulmonary function and age-related decline across the breast cancer survivorship continuum. J Clin Oncol Off J Am Soc Clin Oncol. 2012;30(20):2530–7.

    Article  Google Scholar 

  60. Hubbard G, Adams R, Campbell A, Kidd L, Leslie SJ, Munro J, et al. Is referral of postsurgical colorectal cancer survivors to cardiac rehabilitation feasible and acceptable? A pragmatic pilot randomised controlled trial with embedded qualitative study. BMJ Open. 2016;6(1): e009284.

    Article  PubMed  PubMed Central  Google Scholar 

  61. Dolan LB, Barry D, Petrella T, Davey L, Minnes A, Yantzi A, et al. The cardiac rehabilitation model improves fitness, quality of life, and depression in breast cancer survivors. J Cardiopulm Rehabil Prev. 2018;38(4):246–52.

    Article  PubMed  Google Scholar 

  62. Basen-Engquist K, Alfano CM, Maitin-Shepard M, Thomson CA, Schmitz KH, Pinto BM, et al. Agenda for translating physical activity, nutrition, and weight management interventions for cancer survivors into clinical and community practice. Obes Silver Spring Md. 2017;25(Suppl 2):S9-22.

    Google Scholar 

  63. Courneya KS, Booth CM, Gill S, O’Brien P, Vardy J, Friedenreich CM, et al. The colon health and life-long exercise change trial: a randomized trial of the National Cancer Institute of Canada Clinical Trials Group. Curr Oncol Tor Ont. 2008;15(6):279–85.

    CAS  Google Scholar 

  64. Young-McCaughan S, Mays MZ, Arzola SM, Yoder LH, Dramiga SA, Leclerc KM, et al. Research and commentary: change in exercise tolerance, activity and sleep patterns, and quality of life in patients with cancer participating in a structured exercise program. Oncol Nurs Forum. 2003 Jun;30(3):441–54; discussion 441–454.

  65. Dittus KL, Lakoski SG, Savage PD, Kokinda N, Toth M, Stevens D, et al. Exercise-based oncology rehabilitation: leveraging the cardiac rehabilitation model. J Cardiopulm Rehabil Prev. 2015;35(2):130–9.

    Article  PubMed  PubMed Central  Google Scholar 

  66. De Jesus S, Fitzgeorge L, Unsworth K, Massel D, Suskin N, Prapavessis H, et al. Feasibility of an exercise intervention for fatigued breast cancer patients at a community-based cardiac rehabilitation program. Cancer Manag Res. 2017;9:29–39.

    Article  PubMed  PubMed Central  Google Scholar 

  67. Rothe D, Cox-Kennett N, Buijs DM, Venner CP, Paterson DI, Gyenes GT, et al. Cardiac rehabilitation in patients with lymphoma undergoing autologous hematopoietic stem cell transplantation: a cardio-oncology pilot project. Can J Cardiol. 2018;34(10):S263–9.

    Article  PubMed  Google Scholar 

  68. Hubbard G, Campbell A, Fisher A, Harvie M, Maltinsky W, Mullen R, et al. Physical activity referral to cardiac rehabilitation, leisure centre or telephone-delivered consultations in post-surgical people with breast cancer: a mixed methods process evaluation. Pilot Feasibility Stud. 2018;4:108.

    Article  PubMed  PubMed Central  Google Scholar 

  69. Zvinovski F, Stephens JA, Ramaswamy B, Reinbolt RE, Noonan AM, VanDeusen JB, et al. A cardiac rehabilitation program for breast cancer survivors: a feasibility study. J Oncol. 2021;2021:9965583.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Brigham and Women’s Hospital, Boston, MA, USA

    Alexandra Bili Newman MD & Anju Nohria MD, MSC

  2. University of Texas MD Anderson Cancer Center, Houston, TX, USA

    Karen Basen-Engquist PhD & Susan C. Gilchrist MD

  3. Dana-Farber/Harvard Cancer Center, 450 Brookline Ave, Yawkey 1233, Boston, MA, 02215, USA

    Anju Nohria MD, MSC & Jennifer A. Ligibel MD

  4. Division of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI, USA

    Dennis Kerrigan PhD & Steven J. Keteyian PhD

  5. Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA, USA

    Kathryn H. Schmitz PhD, MPH

Authors
  1. Alexandra Bili Newman MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Karen Basen-Engquist PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Susan C. Gilchrist MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Anju Nohria MD, MSC
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Dennis Kerrigan PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Steven J. Keteyian PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Kathryn H. Schmitz PhD, MPH
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Jennifer A. Ligibel MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jennifer A. Ligibel MD.

Ethics declarations

Conflict of Interest

A Nohria has received research support from Amgen, Inc. and is a consultant for AstraZeneca, Bantam Pharmaceuticals, Boehringer Ingelheim, and Takeda Oncology. J Ligibel has received in-kind product support (to Dana-Farber) from Fitbit and Nestle Health Science in support of the Breast Cancer Weight Loss Study. S Gilchrist reports no conflicts of interest. Of note, after manuscript completion, Dr. Gilchrist started full-time employment with LabCorp. Her employment at LabCorp did not create any new conflicts related to the manuscript. The authors Newman, Basen-Engquist, Kerrigan, Keteyian, and Schmitz report no financial conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This article is part of the Topical Collection on Cardio-oncology

Rights and permissions

Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Newman, A.B., Basen-Engquist, K., Gilchrist, S.C. et al. Exercise and Cardio-Oncology Rehab. Curr Treat Options Cardio Med 24, 183–197 (2022). https://doi.org/10.1007/s11936-022-00968-z

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11936-022-00968-z

Search

Navigation