Abstract
Purpose of review
Advances in display technology and computing have led to new devices capable of overlaying digital information onto the physical world or incorporating aspects of the physical world into virtual scenes. These combinations of digital and physical environments are referred to as extended realities. Extended reality (XR) devices offer many advantages for medical applications including realistic 3D visualization and touch-free interfaces that can be used in sterile environments. This review introduces extended reality and describes how it can be applied to medical practice.
Recent findings
The 3D displays of extended reality devices are valuable in situations where spatial information such as patient anatomy and medical instrument position is important. Applications that take advantage of these 3D capabilities include teaching and pre-operative planning. The utility of extended reality during interventional procedures has been demonstrated with through 3D visualizations of patient anatomy, scar visualization, and real-time catheter tracking with touch-free software control.
Summary
Extended reality devices have been applied to education, pre-procedural planning, and cardiac interventions. These devices excel in settings where traditional devices are difficult to use, such as in the cardiac catheterization lab. New applications of extended reality in cardiology will continue to emerge as the technology improves.
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References and Recommended Reading
Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
The Stanford virtual heart – revolutionizing education on congenital heart defects [Internet]. Available from: https://www.stanfordchildrens.org/en/innovation/virtual-reality/stanford-virtual-heart
Bruckheimer E, Rotschild C, Dagan T, Amir G, Kaufman A, Gelman S, et al. Computer-generated real-time digital holography: first time use in clinical medical imaging. Eur Heart J Cardiovasc Imaging. 2016;17:845–9.
• Silva JN, Southworth MK, Dalal A, Van Hare GF. Improving visualization and interaction during transcatheter ablation using an augmented reality system: first-in-human experience (abstr). Circulation. 2017;136 Our prototype electrophysiology mapping software developed for the Microsoft HoloLens demonstrates the power of XR by visualizing patient-specific 3D anatomy and real-time catheter locations with a completely sterile user interface.
Loy Rodas N, Barrera F, Padoy N. See it with your own eyes: markerless mobile augmented reality for radiation awareness in the hybrid room. IEEE Trans Biomed Eng. 2017;64:429–40.
Doug’s great demo 1968 [Internet]. Available from: http://www.dougengelbart.org/content/view/209/448/
Over 50 years of Moore’s law [Internet]. Available from: https://www.intel.com/content/www/us/en/silicon-innovations/moores-law-technology.html
Milgram P, Kishino F. A taxonomy of mixed reality visual displays. IEICE Trans Inf Syst. 1994;E77-D(12):1321–9.
What is mixed reality? [Internet]. Available from: https://docs.microsoft.com/en-us/windows/mixed-reality/mixed-reality
HoloAnatomy app wins top honors [Internet]. Available from: http://engineering.case.edu/HoloAnatomy-honors
Peterson DC, Mlynarczyk GSA. Analysis of traditional versus three-dimensional augmented curriculum on anatomical learning outcome measures. Anat Sci Educ. 2016;9:529–36. https://doi.org/10.1002/ase.1612
Chan F, Aguirre S, Bauser H. Head tracked stereoscopic pre-surgical evaluation of major aortopulmonary collateral arteries in the newborns. Chicago: Paper presented at: Radiological Society of North America 2013 Scientific Assembly and Annual Meeting; 2013.
Jang J, Tschabrunn CM, Barkagan M, Anter E. Three-dimensional holographic visualization of high-resolution myocardial scar on HoloLens. PLoS One. 2018;13:e0205188. https://doi.org/10.1371/journal.pone.0205188
Kiss G, Palmer CL, Torp H. Patient adapted augmented reality system for real-time echocardiographic applications. In: Linte CA, Yaniv Z, Fallavollita P, editors. Augmented environments for computer-assisted interventions. Cham: Springer International Publishing; 2015. p. 145–54.
Opolski MP, Debski A, Borucki BA, Szpak M, Staruch AD, Kepka C, et al. First-in-man computed tomography-guided percutaneous revascularization of coronary chronic total occlusion using a wearable computer: proof of concept. Can J Cardiol. 2016;32:11–3.
Katz A, Shtub A, Roguin A. Minimizing ionizing radiation exposure in invasive cardiology safety training for medical doctors. J Nucl Eng Radiat Sci. 2017;3:030905.
Linte CA, Moore J, Wedlake C, Bainbridge D, Guiraudon GM, Jones DL, et al. Inside the beating heart: an in vivo feasibility study on fusing pre- and intra-operative imaging for minimally invasive therapy. Int J Comput Assist Radiol Surg. 2009;4:113–23.
Moro C, Štromberga Z, Raikos A, Stirling A. The effectiveness of virtual and augmented reality in health sciences and medical anatomy. Anat Sci Educ. 2017;10:549–59.
Statt N. Realmax’s prototype AR goggles fix one of the HoloLens’ biggest issues. Available from: https://www.theverge.com/2018/1/9/16872110/realmax-ar-goggles-microsoft-hololens-prototype-field-of-view-ces-2018
Vukicevic M, Mosadegh B, Min JK, Little SH. Cardiac 3D printing and its future directions. JACC Cardiovasc Imaging. 2017;10:171–84. https://doi.org/10.1016/j.jcmg.2016.12.001
van der MOAJ, Schijven MP. The value of haptic feedback in conventional and robot-assisted minimal invasive surgery and virtual reality training: a current review. Surg Endosc. 2009;23:1180–90.
King C-H, Culjat MO, Franco ML, Lewis CE, Dutson EP, Grundfest WS, et al. Tactile feedback induces reduced grasping force in robot-assisted surgery. IEEE Trans Haptics. 2009;2:103–10.
Stetten G, Wu B, Klatzky R, Galeotti J, Siegel M, Lee R, et al. Hand-held force magnifier for surgical instruments 2011;90–100.
• Silva JNA, Southworth M, Raptis C, Silva J. Emerging applications of virtual reality in cardiovascular medicine. JACC Basic Transl Sci. 2018;3:420–30. Our previous review of this subject includes additional information about extended reality display hardware.
• Peters TM, Linte CA, Yaniv Z, Williams J. Mixed and Augmented Reality in Medicine: CRC Press; 2018. Readers interested in a thorough treatment of XR in medical practice should consider this book.
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Christopher Andrews, Michael K. Southworth, Jennifer N. A. Silva, and Jonathan R. Silva each report grants from Children’s Discovery Institute and National Institute of Health.
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Andrews, C., Southworth, M.K., Silva, J.N.A. et al. Extended Reality in Medical Practice. Curr Treat Options Cardio Med 21, 18 (2019). https://doi.org/10.1007/s11936-019-0722-7
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DOI: https://doi.org/10.1007/s11936-019-0722-7
Keywords
- Extended reality devices
- Informatics
- Display technology