Permanent His Bundle Pacing for Cardiac Resynchronization

  • William A. Huang
  • Maereg A. Wassie
  • Olujimi A. Ajijola
Arrhythmia (G Upadhyay, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Arrhythmia


His bundle pacing (HBP) has been shown to be a feasible, beneficial, and safe way to achieve cardiac resynchronization therapy (CRT) with recruitment of the heart’s physiological conduction system. HBP should be considered for those with unfavorable coronary sinus (CS) anatomy, and nonresponders to biventricular (BiV) pacing. HBP CRT may also help patients with the nonleft bundle branch block form of conduction delay and heart failure (HF). HBP CRT should be considered strongly in preventing right ventricular (RV) pacing-induced cardiomyopathy, especially after atrioventricular nodal ablation given the discrete nature of the block and the low likelihood of distal block. With increased operator experience and improved lead delivery systems, HBP success rates and safety have improved and are comparable to traditional RV pacing. Battery longevity is also likely comparable to traditional BiV CRT devices. We anticipate the use of HBP CRT growing significantly.


His bundle His bundle pacing CRT Resynchronization Cardiomyopathy 



This work was supported by National Institutes of Health grants HL125730 and DP2HL142045 to OAA.

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflicts of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • William A. Huang
    • 1
  • Maereg A. Wassie
    • 1
  • Olujimi A. Ajijola
    • 1
    • 2
  1. 1.UCLA Cardiac Arrhythmia CenterUniversity of CaliforniaLos AngelesUSA
  2. 2.UCLA Neurocardiology Research CenterDavid Geffen School of Medicine at UCLALos AngelesUSA

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