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Unusual causes of intermittent claudication: Popliteal artery entrapment syndrome, cystic adventitial disease, fibromuscular dysplasia, and endofibrosis

Current Treatment Options in Cardiovascular Medicine volume 11, pages 156–166 (2009)Cite this article

Opinion statement

In the general population, vascular causes of exercise-induced limb discomfort are most often the result of peripheral artery disease (PAD) due to atherosclerosis. However, several other clinical entities can often mimic the symptoms of atherosclerotic PAD of the lower extremities, particularly among younger patients with fewer risk factors for atherosclerosis, who often are more athletically fit than patients with PAD. Treatment for these entities often requires percutaneous or surgical intervention. This article reviews four uncommon vascular causes of exercise-induced limb discomfort: popliteal artery entrapment syndrome, cystic adventitial disease of the popliteal artery, fibromuscular dysplasia of the lower-extremity arteries, and endofibrosis of the iliac artery.

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Affiliations

  1. Section of Vascular Medicine, Division of Cardiovascular Medicine, Massachusetts General Hospital, 55 Fruit Street, Gray-Bigelow 832, Boston, MA, 02114, USA

    Michael R. Jaff

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  1. Ethan C. Korngold
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  2. Michael R. Jaff
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Correspondence to Michael R. Jaff.

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Korngold, E.C., Jaff, M.R. Unusual causes of intermittent claudication: Popliteal artery entrapment syndrome, cystic adventitial disease, fibromuscular dysplasia, and endofibrosis. Curr Treat Options Cardio Med 11, 156–166 (2009). https://doi.org/10.1007/s11936-009-0016-6

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  • DOI: https://doi.org/10.1007/s11936-009-0016-6

Keywords

  • Peripheral Artery Disease
  • Popliteal Artery
  • Critical Limb Ischemia
  • Intermittent Claudication
  • External Iliac Artery