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Male Fertility Preservation

  • Andrology and Infertility (L Lipshultz, Section Editor)
  • Published:
Current Urology Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

With improvements in cancer treatment outcomes and an increase in cancer survivorship, understanding the importance of fertility preservation options prior to undergoing cancer treatment is essential. Therefore, we review herein the effect of cancer and its treatment on male fertility, the rationale for sperm cryopreservation, options for sperm retrieval, ART outcomes, and experimental options.

Recent Findings

Recent data update fertility outcomes with newer cancer therapies and provide longitudinal insight into survivor paternity with and without fertility preservation. Likewise, updated ART outcomes and future preservation options are discussed.

Summary

The effect of cancer and its treatment on spermatogenesis is well established. Sperm cryopreservation is the best pre-treatment insurance for the opportunity of future fertility. Post-therapy patients may also achieve fertility restoration with ART, using cryopreserved or freshly obtained sperm. Meanwhile, utilization of cryopreserved testicular stem cells for future transfer or for in vitro maturation represents exciting alternatives on the horizon.

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  1. Division of Male Reproductive Medicine and Surgery, Scott Department of Urology, Baylor College of Medicine, 6624 Fannin St, Suite 1700, Houston, TX, 77030, USA

    J. Abram McBride & Larry I. Lipshultz

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  1. J. Abram McBride
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J. Abram McBride, M.D. and Larry I. Lipshultz each declare no potential conflicts of interest.

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Abram McBride, J., Lipshultz, L.I. Male Fertility Preservation. Curr Urol Rep 19, 49 (2018). https://doi.org/10.1007/s11934-018-0803-2

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