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Convective Radiofrequency Water Vapor Thermal Therapy with Rezūm System

  • Benign Prostatic Hyperplasia (K McVary, Section Editor)
  • Published:
Current Urology Reports Aims and scope Submit manuscript

Abstract

Purpose

Lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) are amongst the most commonly treated conditions by urologists. Minimally invasive therapies for the treatment of BPH/LUTS have garnered increased interest as new technology has emerged, improving durability, efficacy, and safety. This paper reviews the most recent literature regarding water vapor therapy, a convective thermal therapy that ablates prostatic tissue.

Recent Findings

The current literature includes a pilot study of 65 men and a randomized controlled trial (RCT) of 197 men investigating the efficacy and safety profile of water vapor therapy up to 2 years. Subjects treated with water vapor therapy demonstrated a 51% reduction in IPSS from baseline, sustained at 24 months (p < 0.0001). Durable improvements in max flow rate (Qmax) and quality of life (QoL) were also achieved, while no changes in sexual function were observed. Reporting of adverse events (AEs) reveals predominantly Clavien grade I complications that were self-limited.

Summary

The clinical efficacy and safety of water vapor therapy are durable to 24 months making it an attractive alternative for patients seeking a minimally invasive treatment for LUTS due to BPH.

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Papers of particular interest, published recently, have been highlighted as: • Of importance

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Authors and Affiliations

  1. Division of Urology, Southern Illinois University School of Medicine, St. John’s Pavilion, 301 North Eighth St., P.O. Box 19665, Springfield, IL, 62794-9665, USA

    Sevann Helo, Bradley Holland & Kevin T. McVary

Authors
  1. Sevann Helo
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  2. Bradley Holland
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  3. Kevin T. McVary
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Corresponding author

Correspondence to Kevin T. McVary.

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Conflict of Interest

Sevann Helo and Bradley Holland each declare no potential conflicts of interest.

Kevin T. McVary reports and Lilly/ICOS Self 1/1/11 Present Consultant or Advisor, Scientific Study or Trial, Honorarium, Principal Investigator Y Tadalafil ED and BPHÐIDDK Self 1/1/11 Present Principal Investigator and consultant Y N/A OAB and EDÛoston Scientific (formerly AMS) Self 7/1/13 Present Principal Investigator—Fellowship Grant Y N/A ED and is a section editor for Current Urology Reports.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Benign Prostatic Hyperplasia

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Helo, S., Holland, B. & McVary, K.T. Convective Radiofrequency Water Vapor Thermal Therapy with Rezūm System. Curr Urol Rep 18, 78 (2017). https://doi.org/10.1007/s11934-017-0728-1

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  • DOI: https://doi.org/10.1007/s11934-017-0728-1

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