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Near-Infrared Fluorescence Imaging with Intraoperative Administration of Indocyanine Green for Robotic Partial Nephrectomy

  • New Imaging Techniques (A Rastinehad and S Rais-Bahrami, Section Editors)
  • Published:
Current Urology Reports Aims and scope Submit manuscript

Abstract

Near-infrared fluorescence (NIRF) imaging with intraoperative administration of indocyanine green (ICG) is a technology with emerging applications in urologic surgery. ICG is a water-soluble dye that fluoresces bright green when viewed under near-infrared light (700–1000 nm). This technology has been applied to robotic partial nephrectomy, first to potentially allow for the differentiation of renal tumor from normal parenchyma. In this application, it has been hypothesized that normal kidney tissue fluoresces green, while the tumor commonly remains hypofluorescent, thereby aiding tumor excision. Secondly, NIRF imaging with ICG has been employed to facilitate selective arterial clamping during robotic partial nephrectomy, allowing for a regional perfusion deficit in the kidney to be readily identified and therefore targeted at a given tumor. Recent studies have shown the associated decrease in global ischemia to minimize resultant loss of renal function at certain time endpoints. This review presents the most recent studies and evidence on the intraoperative administration of indocyanine green for robotic partial nephrectomy.

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Conflict of Interest

Dr. Marc A. Bjurlin and Dr. Tyler R. McClintock each declare no potential conflicts of interest.

Dr. Michael D. Stifelman is a consultant for Vascular Technology Inc. and Surgiquest and a lecturer/ownership of Intuitive Surgical, Inc.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Disclosures

MAB: none

TRM: none

MDS: Consultant VTI, Consultant Surgiquest, Lecturer/Ownership Intuitive Surgical, Inc.

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Authors and Affiliations

  1. Division of Urology, Department of Surgery, SBH Health System, Bronx, NY, USA

    Marc A. Bjurlin

  2. Division of Urology, Department of Surgery, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

    Tyler R. McClintock

  3. Department of Urology, New York University, Langone Medical Center, 150 East 32nd Street, 2nd Floor, New York, NY, 10016, USA

    Michael D. Stifelman

Authors
  1. Marc A. Bjurlin
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  2. Tyler R. McClintock
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  3. Michael D. Stifelman
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Correspondence to Michael D. Stifelman.

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This article is part of the Topical Collection on New Imaging Techniques

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Bjurlin, M.A., McClintock, T.R. & Stifelman, M.D. Near-Infrared Fluorescence Imaging with Intraoperative Administration of Indocyanine Green for Robotic Partial Nephrectomy. Curr Urol Rep 16, 20 (2015). https://doi.org/10.1007/s11934-015-0495-9

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  • DOI: https://doi.org/10.1007/s11934-015-0495-9

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