Current Urology Reports

, 15:440 | Cite as

Lower Urinary Tract Symptoms in Women with Diabetes Mellitus: A Current Review

  • Rebecca James
  • Adonis Hijaz
Lower Urinary Tract Symptoms & Voiding Dysfunction (H Goldman and G Badlani, Section Editors)
Part of the following topical collections:
  1. Topical Collection on Lower Urinary Tract Symptoms & Voiding Dysfunction


A literature review of the most current publications studying lower urinary tract symptoms (LUTS) and findings in diabetic women was conducted including articles from January 2013 to April 2014. Current reports consistently note that aging and obesity are significantly associated with worsened LUTS in diabetic women. Glucosuria has variable effects on urodynamic parameters and LUTS, but has a significant association with urinary tract infection (UTI) and incontinence at clinically relevant numbers, such as HbA1C values. The presence of severe nocturia in diabetic patients warrants careful surveillance for cardiovascular risks given the significant association with mortality. Diabetics appear to be at higher risk for colonization with the virulent, extended-spectrum, β-lactamase-producing Escherichia coli and Klebsiella species in UTI. Novel therapies in glycemic control and for diabetic bladder dysfunction are undergoing animal model trials with encouraging results. The most promising of these includes stem cell therapy, although a need exists for human studies.


Diabetes mellitus and lower urinary tract symptoms Stress urinary incontinence Urge incontinence Overactive bladder Urinary frequency Urgency Nocturia 


Compliance with Ethics Guidelines

Conflict of Interest

Dr. Rebecca James and Dr. Adonis Hijaz each declare no potential conflicts of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Female Pelvic Medicine and Reconstructive Surgery, Department of UrologyUniversity Hospitals Case Medical CenterClevelandUSA
  2. 2.Department of UrologyUniversity Hospitals Case Medical CenterClevelandUSA

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