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Current Status of Salvage Robot-Assisted Laparoscopic Prostatectomy for Radiorecurrent Prostate Cancer

  • Endourology (V Bird, Section Editor)
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Abstract

Radiation therapy (RT) is one of the treatment options for prostate cancer (PCa). Transperineal low–dose rate brachytherapy (BT) is another safe and effective technique for low-risk PCa. Recurrence after RT for localized PCa can be defined by a PSA value of 2 ng/mL above the nadir after RT, and biochemical recurrence (BCR) rate after RT is 40–60 %. In case of radiorecurrent PCa, treatment options include salvage radical prostatectomy (RP), cryotherapy, high-intensity focused ultrasound (HIFU), and salvage BT. Only salvage RP has cancer control results for over 10-year follow-up in a substantial portion of patients (30–40 %). However, salvage RP is technically demanding, and experienced surgeons are needed; in fact, RT-induced cystitis, fibrosis, and tissue plane obliteration can lead to significant complications, such as rectal injuries, anastomotic stricture, and urinary incontinence. This review describes indications, oncologic and functional outcomes, surgical techniques, and complications of salvage robot-assisted RP.

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No potential conflicts of interest relevant to this article were reported.

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Authors and Affiliations

  1. Clinica Urologica I, Università degli Studi di Milano, Fondazione IRCCS Ca’ Granda - Ospedale Maggiore Policlinico, Milan, Italy

    Bernardo Rocco, Gabriele Cozzi, Matteo Giulio Spinelli, Angelica Grasso & Daniela Varisco

  2. Global Robotics Institute, Florida Hospital–Celebration Health, University of Central Florida School of Medicine, Celebration, FL, USA

    Rafael F. Coelho & Vipul R. Patel

  3. Hospital Israelita Albert Einstein, Sao Paulo, Brazil

    Rafael F. Coelho

  4. Instituto do Câncer do Estado de Sao Paulo, Sao Paulo, Brazil

    Rafael F. Coelho

Authors
  1. Bernardo Rocco
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  2. Gabriele Cozzi
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  3. Matteo Giulio Spinelli
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  4. Angelica Grasso
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  5. Daniela Varisco
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  6. Rafael F. Coelho
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  7. Vipul R. Patel
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Correspondence to Gabriele Cozzi.

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Rocco, B., Cozzi, G., Spinelli, M.G. et al. Current Status of Salvage Robot-Assisted Laparoscopic Prostatectomy for Radiorecurrent Prostate Cancer. Curr Urol Rep 13, 195–201 (2012). https://doi.org/10.1007/s11934-012-0245-1

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  • DOI: https://doi.org/10.1007/s11934-012-0245-1

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