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Salvage therapy for prostate cancer recurrence after radiation therapy

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Abstract

Radiotherapy has been successful in treating localized prostate cancer; however, a subset of patients will experience disease recurrence. Determination of the recurrence location must be made using pretreatment and posttreatment clinical variables, imaging, and postradiotherapy biopsy. Patients presumed to have local-only recurrence, optimal clinical risk factors, and an extended life expectancy may be considered for salvage local treatment. Current options include salvage surgery, cryoablation, and brachytherapy. Although they are associated with higher morbidity than primary therapy, salvage treatments can be effective and can still provide patients with a good oncologic and functional outcome. As these modalities continue to improve and patient selection is optimized, better results will evolve.

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Authors and Affiliations

  1. Division of Urology, University of Alabama at Birmingham, 1530 3rd Avenue South, FOT 1105, Birmingham, AL, 35294, USA

    J. Erik Busby

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  1. Jared M. Cox
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Correspondence to J. Erik Busby.

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Cox, J.M., Busby, J.E. Salvage therapy for prostate cancer recurrence after radiation therapy. Curr Urol Rep 10, 199–205 (2009). https://doi.org/10.1007/s11934-009-0034-7

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  • DOI: https://doi.org/10.1007/s11934-009-0034-7

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