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Biomarkers for the detection and prognosis of prostate cancer

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Abstract

Recent studies have cast doubt on the reliability of serum total prostate-specific antigen as a biomarker for the detection and prognosis of prostate cancer. Biomarkers that can identify those men at risk for clinically significant prostate cancer are desperately needed. The search for biomarkers that may improve the detection of biologically consequential prostate cancer is one of the most active areas under current investigation. In this review, we highlight some of these ongoing efforts. Proper validation of newly discovered biomarkers is of paramount importance.

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  1. Department of Urology, University of Texas Health Sciences Center, Floyd Curl Drive, A7703, 78229, San Antonio, TX, USA

    Javier Hernandez MD

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  1. Javier Hernandez MD
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  2. Edith Canby-Hagino MD
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  3. Ian M. Thompson MD
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Hernandez, J., Canby-Hagino, E. & Thompson, I.M. Biomarkers for the detection and prognosis of prostate cancer. Curr Urol Rep 6, 171–176 (2005). https://doi.org/10.1007/s11934-005-0004-7

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