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Plaque incision and grafting represents the best surgical approach to the Peyronie’s disease patient: Con

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Abstract

Surgical treatment options for Peyronie’s disease include tunica shortening (Nesbit and plication) and grafting procedures. Tunica shortening procedures are associated with penile shortening. However, the amount of penile shortening is rarely significant for the patient. Although grafting procedures aim to prevent penile shortening, this may still be an issue due to the pathologic extent of Peyronie’s disease. Long-term postoperative erectile dysfunction is the major drawback. Many types of grafting material have been used, but only saphenous vein has gained certain acceptance. Grafting procedures must be restricted to patients with normal preoperative erectile status and excessive curvature. Nesbit or plication procedures may be associated with significant penile shortening. Grafting procedures are also indicated in cases of hourglass deformities, because they cannot be corrected by the Nesbit procedure. Nesbit wedge resection is still the gold standard for treating Peyronie’s disease.

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References and Recommended Reading

  1. Gelbard MK, Dorey F, James K: The natural history of Peyronie’s disease. J Urol 1990, 144:1376–1379.

    PubMed  CAS  Google Scholar 

  2. Devine CJ, Jr., Somers KD, Jordan SG, et al.: Proposal: trauma as the cause of the Peyronie’s lesion. J Urol 1997, 157:285–290.

    Article  PubMed  Google Scholar 

  3. El-Sakka AI, Hassoba HM, Pillarisetty RJ, et al.: Peyronie’s disease is associated with an increase in transforming growth factor-beta protein expression. J Urol 1997, 158:1391–1394.

    Article  PubMed  CAS  Google Scholar 

  4. Pryor J, Akkus E, Alter G, et al.: Peyronie’s Disease. J Sex Med 2004, 1:110–115.

    Article  PubMed  Google Scholar 

  5. Rehman J, Benet A, Minsky LS, et al.: Results of surgical treatment for abnormal penile curvature: Peyronie’s disease and congenital deviation by Modified Nesbit plication (tunical shaving and plication). J Urol 1997, 157:1288–1291.

    Article  PubMed  CAS  Google Scholar 

  6. Bailey MJ, Yande S, Walmsley B, et al.: Surgery for Peyronie’s disease. A review of 200 patients. Br J Urol 1985, 57:746–749.

    Article  PubMed  CAS  Google Scholar 

  7. Metz P, Ebbehoj J, Uhrenholdt A, et al.: Peyronie’s disease and erectile failure. J Urol 1983, 130:1103–1104.

    PubMed  CAS  Google Scholar 

  8. Poulsen J, Kirkeby HJ: Treatment of penile curvature: a retrospective study of 175 patients operated with plication of the tunica albuginea or with the Nesbit procedure. Br J Urol 1995, 75:370–374.

    Article  PubMed  CAS  Google Scholar 

  9. Pryor JP, Fitzpatrick JM: A new approach to the correction of the penile deformity in Peyronie’s disease. J Urol 1979, 122:622–623.

    PubMed  CAS  Google Scholar 

  10. Ralph DJ, al-Akraa M, Pryor JP: The Nesbit operation for Peyronie’s disease: 16-year experience. J Urol 1995, 154:1362–1363.

    Article  PubMed  CAS  Google Scholar 

  11. Ebbehoj J, Metz P: Congenital penile angulation. Br J Urol 1987, 60:264–266.

    Article  PubMed  CAS  Google Scholar 

  12. Savoca G, Trombetta C, Ciampalini S, et al.: Long-term results with Nesbit’s procedure as treatment of Peyronie’s disease. Int J Impot Res 2000, 12:289–293.

    Article  PubMed  CAS  Google Scholar 

  13. Yachia D: Modified corporoplasty for the treatment of penile curvature. J Urol 1990, 143:80–82.

    PubMed  CAS  Google Scholar 

  14. Donatucci CF, Lue TF: Correction of penile deformity assisted by intracavernous injection of papaverine. J Urol 1992, 147:1108–1110.

    PubMed  CAS  Google Scholar 

  15. Sulaiman MN, Gingell JC: Nesbit’s procedure for penile curvature. J Androl 1994, 15(Suppl):S54-S56.

    Google Scholar 

  16. Syed AH, Abbasi Z, Hargreave TB: Nesbit procedure for disabling Peyronie’s curvature: a median follow-up of 84 months. Urology 2003, 61:999–1003.

    Article  PubMed  Google Scholar 

  17. Savoca G, Scieri F, Pietropaolo F, et al.: Straightening corporoplasty for Peyronie’s disease: a review of 218 patients with median follow-up of 89 months. Eur Urol 2004, 46:610–614.

    Article  PubMed  Google Scholar 

  18. Nooter RI, Bosch JL, Schroder FH: Peyronie’s disease and congenital penile curvature: long-term results of operative treatment with the plication procedure. Br J Urol 1994, 74:497–500.

    Article  PubMed  CAS  Google Scholar 

  19. Klevmark B, Andersen M, Schultz A, et al.: Congenital and acquired curvature of the penis treated surgically by plication of the tunica albuginea. Br J Urol 1994, 74:501–506.

    Article  PubMed  CAS  Google Scholar 

  20. Kummerling S, Schubert J: Peyronie’s disease. Investigation of staging, erectile failure and operative management. Int Urol Nephrol 1995, 27:629–637.

    Article  PubMed  CAS  Google Scholar 

  21. Thiounn N, Missirliu A, Zerbib M, et al.: Corporeal plication for surgical correction of penile curvature. Experience with 60 patients. Eur Urol 1998, 33:401–404.

    Article  PubMed  CAS  Google Scholar 

  22. Schultheiss D, Meschi MR, Hagemann J, et al.: Congenital and acquired penile deviation treated with the essed plication method. Eur Urol 2000, 38:167–171.

    Article  PubMed  CAS  Google Scholar 

  23. Chahal R, Gogoi NK, Sundaram SK, et al.: Corporal plication for penile curvature caused by Peyronie’s disease: the patients’ perspective. BJU Int 2001, 87:352–356.

    Article  PubMed  CAS  Google Scholar 

  24. Cormio L, Zizzi V, Bettocchi C, et al.: Tunica albuginea plication for the correction of penile curvature. Scand J Urol Nephrol 2002, 36:307–310.

    Article  PubMed  CAS  Google Scholar 

  25. van der Drift DG, Vroege JA, Groenendijk PM, et al.: The plication procedure for penile curvature: surgical outcome and postoperative sexual functioning. Urol Int 2002, 69:120–124.

    Article  PubMed  Google Scholar 

  26. Gholami SS, Lue TF: Correction of penile curvature using the 16-dot plication technique: a review of 132 patients. J Urol 2002, 167:2066–2069.

    Article  PubMed  Google Scholar 

  27. Van Der Horst C, Martinez Portillo FJ, Seif C, et al.: Treatment of penile curvature with Essed-Schroder tunical plication: aspects of quality of life from the patients’ perspective. BJU Int 2004, 93:105–108.

    Article  Google Scholar 

  28. Gholami SS, Lue TF: Peyronie’s disease. Urol Clin North Am 2001, 28:377–390.

    Article  PubMed  CAS  Google Scholar 

  29. Devine CJ, Jr., Horton CE: Surgical treatment of Peyronie’s disease with a dermal graff. J Urol 1974, 111:44–49.

    PubMed  Google Scholar 

  30. Brannigan RE, Kim ED, Oyasu R, et al.: Comparison of tunica albuginea substitutes for the treatment of Peyronie’s disease. J Urol 1998, 159:1064–1068.

    Article  PubMed  CAS  Google Scholar 

  31. Fournier GR, Jr., Lue TF, Tanagho EA: Peyronie’s plaque: surgical treatment with the carbon dioxide laser and a deep dorsal vein patch graft. J Urol 1993, 149:1321–1325.

    PubMed  Google Scholar 

  32. Brock G, Nunes L, von Heyden B, et al.: Can a venous patch graft be a substitute for the tunica albuginea of the penis? J Urol 1993, 150:1306–1309.

    PubMed  CAS  Google Scholar 

  33. Schiffman ZJ, Gursel EO, Laor E: Use of Dacron patch graft in Peyronie disease. Urology 1985, 25:38–40.

    Article  PubMed  CAS  Google Scholar 

  34. Faerber GJ, Konnak JW: Results of combined Nesbit penile plication with plaque incision and placement of Dacron patch in patients with severe Peyronie’s disease. J Urol 1993, 149:1319–1320.

    PubMed  CAS  Google Scholar 

  35. Ganabathi K, Dmochowski R, Zimmern PE, et al.: Peyronie’s disease: surgical treatment based on penile rigidity. J Urol 1995, 153:662–666.

    Article  PubMed  CAS  Google Scholar 

  36. Krishnamurti S: Penile dermal flap for defect reconstruction in Peyronie’s disease: operative technique and four years’ experience in 17 patients. Int J Impot Res 1995, 7:195–208.

    PubMed  CAS  Google Scholar 

  37. Gelbard MK, Hayden B: Expanding contractures of the tunica albuginea due to Peyronie’s disease with temporalis fascia free grafts. J Urol 1991, 145:772–776.

    PubMed  CAS  Google Scholar 

  38. Das S: Peyronie’s disease: excision and autografting with tunica vaginalis. J Urol 1980, 124:818–819.

    PubMed  CAS  Google Scholar 

  39. Fallon B: Cadaveric dura mater graft for correction of penile curvature in Peyronie disease. Urology 1990, 35:127–129.

    Article  PubMed  CAS  Google Scholar 

  40. Hellstrom WJ, Reddy S: Application of pericardial graft in the surgical management of Peyronie’s disease. J Urol 2000, 163:1445–1447.

    Article  PubMed  CAS  Google Scholar 

  41. Chun JL, McGregor A, Krishnan R, et al.: A comparison of dermal and cadaveric pericardial grafts in the Modified Horton-Devine procedure for Peyronie’s disease. J Urol 2001, 166:185–188.

    Article  PubMed  CAS  Google Scholar 

  42. Levine LA, Estrada CR: Human cadaveric pericardial graft for the surgical correction of Peyronie’s disease. J Urol 2003, 170:2359–2362.

    Article  PubMed  Google Scholar 

  43. Bruschini H, Mitre AI: Peyronie disease: surgical treatment with muscular aponeurosis. Urology 1979, 13:505–506.

    Article  PubMed  CAS  Google Scholar 

  44. Knoll LD: Use of porcine small intestinal submucosal graft in the surgical management of Peyronie’s disease. Urology 2001, 57:753–757.

    Article  PubMed  CAS  Google Scholar 

  45. Shioshvili TJ, Kakonashvili AP: The surgical treatment of Peyronie’s disease: replacement of plaque by free autograft of buccal mucosa. Eur Urol 2005, 48:129–133.

    Article  PubMed  Google Scholar 

  46. El-Sakka AI, Rashwan HM, Lue TF: Venous patch graft for Peyronie’s disease. Part II: outcome analysis. J Urol 1998, 160:2050–2053.

    Article  PubMed  CAS  Google Scholar 

  47. Kadioglu A, Tefekli A, Usta M, et al.: Surgical treatment of Peyronie’s disease with incision and venous patch technique. Int J Impot Res 1999, 11:75–81.

    Article  PubMed  CAS  Google Scholar 

  48. Montorsi F, Salonia A, Maga T, et al.: Evidence based assessment of long-term results of plaque incision and vein grafting for Peyronie’s disease. J Urol 2000, 163:1704–1708.

    Article  PubMed  CAS  Google Scholar 

  49. Akkus E, Ozkara H, Alici B, et al.: Incision and venous patch graft in the surgical treatment of penile curvature in Peyronie’s disease. Eur Urol 2001, 40:531–536.

    Article  PubMed  CAS  Google Scholar 

  50. Adeniyi AA, Goorney SR, Pryor JP, et al.: The Lue procedure: an analysis of the outcome in Peyronie’s disease. BJU Int 2002, 89:404–408.

    Article  PubMed  CAS  Google Scholar 

  51. Chang JA, Gholami SS, Lue TF: Surgical management: saphenous vein grafts. Int J Impot Res 2002, 14:375–378.

    Article  PubMed  CAS  Google Scholar 

  52. Teloken C, Grazziotin T, Rhoden E, et al.: Penile straightening with crural graft of the corpus cavernosum. J Urol 2000, 164:107–108.

    Article  PubMed  CAS  Google Scholar 

  53. Hatzichristou DG, Hatzimouratidis K, Apostolidis A, et al.: Corporoplasty using tunica albuginea free grafts for penile curvature: surgical technique and long-term results. J Urol 2002, 167:1367–1370.

    Article  PubMed  Google Scholar 

  54. Schwarzer JU, Muhlen B, Schukai O: Penile corporoplasty using tunica albuginea free graft from proximal corpus cavernosum: a new technique for treatment of penile curvature in Peyronie’s disease. Eur Urol 2003, 44:720–723.

    Article  PubMed  Google Scholar 

  55. Hellstrom WJ, Usta MF: Surgical approaches for advanced Peyronie’s disease patients. Int J Impot Res 2003, 15(Supp l5):S121-S124.

    Article  PubMed  Google Scholar 

  56. Dalkin BL, Carter MF: Venogenic impotence following dermal graft repair for Peyronie’s disease. J Urol 1991, 146:849–851.

    PubMed  CAS  Google Scholar 

  57. Carson CC, Chun JL: Peyronie’s disease: surgical management: autologous materials. Int J Impot Res 2002, 14:329–335.

    Article  PubMed  CAS  Google Scholar 

  58. Collins JP: Experience with lyophilized human dura for treatment of Peyronie disease. Urology 1988, 31:379–381.

    Article  PubMed  CAS  Google Scholar 

  59. Schultheiss D, Lorenz RR, Meister R, et al.: Functional tissue engineering of autologous tunica albuginea: a possible graft for Peyronie’s disease surgery. Eur Urol 2004, 45:781–786.

    Article  PubMed  Google Scholar 

  60. Lue TF, El-Sakka AI: Venous patch graft for Peyronie’s disease. Part I: technique. J Urol 1998, 160:2047–2049.

    Article  PubMed  CAS  Google Scholar 

  61. Montorsi F, Briganti A, Da Posso L, et al.: Five years followup of plaque incision and vein grafting for peyronie’s disease. Int J Impot Res 2003, 15:S14 (MP13–18).

    Google Scholar 

  62. Jordan GH, Angermeier KW: Preoperative evaluation of erectile function with dynamic infusion cavernosometry/ cavernosography in patients undergoing surgery for Peyronie’s disease: correlation with postoperative results. J Urol 1993, 150:1138–1142.

    PubMed  CAS  Google Scholar 

  63. Levine L, Greenfield J, Estrada CR: Erectile dysfunction following surgical correction of Peyronie’s disease and a pilot study of the use of sildenafil citrate rehabilitation for postoperative erectile dysfunction. J Sexual Medicine 2005, 2:241–247.

    Article  Google Scholar 

  64. Licht MR, Lewis RW: Modified Nesbit procedure for the treatment of Peyronie’s disease: a comparative outcome analysis. J Urol 1997, 158:460–463.

    Article  PubMed  CAS  Google Scholar 

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  1. Center for Sexual and Reproductive Health, Papageorgiou General Hospital, Aristotle University of Thessaloniki, 77 Mitropoleos Street, 54622, Thessaloniki, Greece

    Dimitrios G. Hatzichristou MD

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  1. Konstantinos Hatzimouratidis MD
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  2. Dimitrios G. Hatzichristou MD
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Correspondence to Dimitrios G. Hatzichristou MD.

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Hatzimouratidis, K., Hatzichristou, D.G. Plaque incision and grafting represents the best surgical approach to the Peyronie’s disease patient: Con. Current Sexual Health Reports 3, 56–60 (2006). https://doi.org/10.1007/s11930-996-0003-9

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