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Cytokines and the immunopathology of the spondyloarthropathies

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Abstract

In contrast to rheumatoid arthritis (RA), the triggering antigens are known in reactive arthritis (ReA) and Lyme arthritis. Thus, in these arthritides the antigen-specific T-cell response can be investigated in much detail and lessons possibly learned for other spondyloarthropathies (SpA) such as ankylosing spondylitis (AS) where T cells may well also play an important role in the pathogenesis. This article focusses on the immunopathology of the SpA, ReA, and AS with special reference to T cells and cytokines.

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  1. Department of Medicine, Rheumatology, Klinikum Benjamin Franklin, Free University, Hindenburgdamm 30, 12200, Berlin, Germany

    Jürgen Braun MD & Joachim Sieper MD

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Braun, J., Sieper, J. Cytokines and the immunopathology of the spondyloarthropathies. Curr Rheumatol Rep 1, 67–77 (1999). https://doi.org/10.1007/s11926-999-0028-y

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