References
Cohen H, Doré CJ, Clawson S, Hunt BJ, Isenberg D, Khamashta M, et al. Rivaroxaban in antiphospholipid syndrome (RAPS) protocol: a prospective, randomized controlled phase II/III clinical trial of rivaroxaban versus warfarin in patients with thrombotic antiphospholipid syndrome, with or without SLE. Lupus. 2015;24:1087–94. doi:10.1177/0961203315581207.
Green L, Lawrie AS, Patel S, Hossain F, Chitolie A, Mackie IJ, et al. The impact of elective knee/hip replacement surgery and thromboprophylaxis with rivaroxaban or dalteparin on thrombin generation. Br J Haematol. 2010;151:469–76. doi:10.1111/j.1365-2141.2010.08433.x.
Eerenberg ES, Kamphuisen PW, Sijpkens MK, Meijers JC, Buller HR, Levi M. Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects. Circulation. 2011;124:1573–9. doi:10.1161/CIRCULATIONAHA.111.029017.
Arachchillage DRJ, Efthymiou M, Mackie IJ, Lawrie AS, Machin SJ, Cohen H. Rivaroxaban and warfarin achieve effective anticoagulation, as assessed by inhibition of TG and in-vivo markers of coagulation activation, in patients with venous thromboembolism. Thromb Res. 2015;135:388–93. doi:10.1016/j.thromres.2014.11.037.
Zuily S, Regnault V, Guillemin F, Kaminsky P, Rat A-C, Lecompte T, et al. Superficial vein thrombosis, thrombin generation and activated protein C resistance as predictors of thromboembolic events in lupus and antiphospholipid patients. A prospective cohort study. Thromb Res. 2013;132:e1–7. doi:10.1016/j.thromres.2013.04.012.
Pengo V, Ruffatti A, Legnani C, Testa S, Fierro T, Marongiu F, et al. Incidence of a first thromboembolic event in asymptomatic carriers of high-risk antiphospholipid antibody profile: a multicenter prospective study. Blood. 2011;118:4714–8. doi:10.1182/blood-2011-03-340232.
Erkan D, Zuily S, Banzato A, De Ceulaer K, Cohen H, Tektonidou M, et al. Antiphospholipid syndrome alliance for clinical trials and international networking clinical database and repository (“registry”) prospective follow-up analysis: one-year first and recurrent thrombosis risk. Arthritis Rheum. 2015;67
Crowley MP, Cuadrado MJ, Hunt BJ. Catastrophic antiphospholipid syndrome on switching from warfarin to rivaroxaban. Thromb Res. 2017;153:37–9. doi:10.1016/j.thromres.2017.03.006.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Funding
None.
Conflict of Interest
The authors declare that they have no conflict of interest.
Additional information
This reply refers to the comment available at http://dx.doi.org/10.1007/s11926-017-0675-3
Rights and permissions
About this article
Cite this article
Dufrost, V., Risse, J., Wahl, D. et al. Direct Oral Anticoagulants Use in Antiphospholipid Syndrome: Are These Drugs an Effective and Safe Alternative to Warfarin? A Systematic Review of the Literature: Response to Comment. Curr Rheumatol Rep 19, 52 (2017). https://doi.org/10.1007/s11926-017-0676-2
Published:
DOI: https://doi.org/10.1007/s11926-017-0676-2