Food, Drink, and Herbs: Alternative Therapies and Gout
- 1.5k Downloads
Gout was first recognized as a distinct clinical entity in antiquity. Our understanding of the epidemiology and treatment of gout has evolved over millennia intertwined with observations about social class and plant and animal sources of food, beverages and medicines. Investigators have identified various aspects of diet that relate to gout risk and recurrence. Some of our most useful medications for the treatment of gout were developed from herbal precursors. Traditional dietary recommendations for gout patients have included limiting high purine meat and alcohol consumption. More recent work suggests diets leading to weight loss through calorie and carbohydrate reductions may be effective for lowering serum urate levels, as well as the risk of gout.
KeywordsGout Diet Herbal medicine Herbs Complementary and alternative medicine CAM Alcohol Vitamin C Acupuncture
Compliance with Ethics Guidelines
Conflict of Interest
Sharon L. Kolasinski declares that she has no conflict of interest.
Human and Animal Rights and Informed Consent
This article does not contain any studies with human or animal subjects performed by the author.
Papers of particular interest, published recently, have been highlighted as: • Of importance
- 3.•Zhang Y, Chen C, Choi H, Chaisson C, Hunter D, Niu J, et al. Purine-rich foods intake and recurrent gout attacks. Ann Rheum Dis. 2012;71:1448–53. One of a number of studies from the Boston University Online Case-Crossover Study of Triggers for Recurrent Gout Attacks clarifying the relationship of dietary factors long associated with the occurrence of gout flares using an innovative online technique for gathering diet related data.Google Scholar
- 5.Dessein PH, Shipton EA, Stanwix AE. JoffeBI and J Ramokgadi. Beneficial effects of weight loss associated with moderate calorie/carbohydrate restriction, and increased proportional intake of protein and unsaturated fat on serum urate and lipoprotein levels in gout: a pilot study. Ann Rheum Dis. 2000;59:539–43.PubMedCentralPubMedCrossRefGoogle Scholar
- 6.Kontogianni MD, Chrysohoou C, Panagiotakos DB, Tsetsekou E, Zeimbekis A, Pitsavos C, et al. Adherence to the Mediterranean diet and serum uric acid: the ATTICA study. Scand J Rheumatol. 2012;41:442–9.Google Scholar
- 11.•Zhang Y, Neogi T, Chen C, Chaisson C, Hunter DJ, Choi HK. Cherry consumption and decreased risk of recurrent gout attacks. Arthritis Rheum. 2012;64:4004–11. Interesting prospective verification of the utility of the folk practice of consuming cherries to prevent gout attacks.PubMedCentralPubMedCrossRefGoogle Scholar
- 12.Gaffo AL, Roseman JM, Jacobs DR, Lewis CE, Shikany JM, Mikuls TR, et al. Serum urate and its relationship with alcoholic beverage intake in men and women: findings from the Coronary Artery Risk Development in Young Adults (CARDIA) cohort. Ann Rheum Dis. 2010;69:1965–70.Google Scholar
- 13.Lee SJ, Terkeltaub RA and A Kavanaugh. Recent developments in diet and gout. Curr Opin Rheumatol 18:193-198.Google Scholar
- 17.Zgaga L, Theodoratou E, Kyle J, Farrington SM, Agakov F, Tenesa A, Walker M, McNeill G, Wright AF, Rudan I, Dunlop MG and H Campbell. The association of dietary intake of purine-rich vegetables, sugar-sweetened beverages and dairy with plasma urate, in a cross-sectional study. PLoS ONE 7(6): e38123. doi: 10.1371/journal.pone.0038123.
- 21.•Stamp LK, O’Donnell JL, Frampton C, Drake JM, Zhang M, Chapman PT. Clinically insignificant effect of supplemental vitamin C on serum urate in patients with gout. Arthritis Rheum. 2013;65:1636–42. Prospective, randomized controlled trial of vitamin C supplementation in gout patients underscores the complex mechanisms by which uric acid is handled in the body and how ingested substances might affect clinical endpoints, as well as the difficulty of trial design with subjects on varied medications.PubMedCrossRefGoogle Scholar
- 24.Zhang S, Liu J, He K. Treatment of acute gouty arthritis by blood-letting cupping and herbal medicine. J TCM. 2010;30:18–20.Google Scholar
- 28.Genuis SJ, Schwalfenberg G, Siy AJ and I Rodushkin. Toxic element contamination of natural health products and pharmaceutical preparations. Plos ONE 7(11):e49676.Google Scholar