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Immunogenicity of biologic agents: A new concern for the practicing rheumatologist?

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References

  1. Baert F, Noman M, Vermeire S, et al.: Influence of immunogenicity on the long term efficacy of infliximab in Crohn’s disease. N Engl J Med 2003, 348:601–608.

    Article  PubMed  CAS  Google Scholar 

  2. Haraoui B, Cameron L, Ouellet M, et al.: Anti-infliximab antibodies in patients with rheumatoid arthritis who require higher doses of infliximab to achieve or maintain a clinical response. J Rheumatol 2006, 33:31–36.

    PubMed  CAS  Google Scholar 

  3. Weiner LM: Fully human therapeutic monoclonal antibodies. J Immunother 2006, 29:1–9.

    Article  PubMed  CAS  Google Scholar 

  4. Abbott Laboratories: Humira® (adalimumab) prescribing information. Available at http://www.rxabbort.com/pdf/humira.pdf. Accessed on May 14, 2007.

  5. Cohen SB, Greenwald M, Dougados M, et al.: Efficacy and safety of Rituximab in active RA patients who experienced an inadequate response to one or more anti-TNF alpha therapies (REFLEX Study) [abstract]. Arthritis Rheum 2005, 52:S677.

    Google Scholar 

  6. Klareskog L, Wajdula J, Baker P, et al.: Low and transient auto and anti-etanercept antibody formation has no measurable impact on clinical outcomes during 5 years of etanercept treatment in patients with rheumatoid arthritis [abstract]. Ann Rheum Dis 2006, 65:325.

    Article  Google Scholar 

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Correspondence to Boulos Haraoui MD.

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Haraoui, B., Pelletier, JP. & Martel-Pelletier, J. Immunogenicity of biologic agents: A new concern for the practicing rheumatologist?. Curr Rheumatol Rep 9, 265–267 (2007). https://doi.org/10.1007/s11926-007-0042-x

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