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Management of virus-induced systemic vasculitides

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Abstract

The best therapeutic strategy in virus-induced vasculitides should take into account the etiology of the disease and be adapted to the pathogenesis. The combination of antiviral treatments and plasma exchanges has been proven effective in polyarteritis nodosa. In HIV-related vasculitis, this strategy is effective and does not jeopardize the outcome of AIDS, as do cytotoxic agents. In vasculitis related to hepatitis C virus-associated cryoglobulinemia, plasma exchanges improve the outcome, but the poor effectiveness of antiviral drugs usually does not favor a definite recovery of the patients. Relapses are frequent.

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Authors and Affiliations

  1. Department of Internal Medicine, Hôpital Avicenne, AP-HP, Université Paris-Nord, 125 rue de Stalingrad, 93009, Bobigny Cedex, France

    Loïc Guillevin MD & Pascal Cohen MD

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  1. Loïc Guillevin MD
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  2. Pascal Cohen MD
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Guillevin, L., Cohen, P. Management of virus-induced systemic vasculitides. Curr Rheumatol Rep 4, 60–66 (2002). https://doi.org/10.1007/s11926-002-0025-x

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  • DOI: https://doi.org/10.1007/s11926-002-0025-x

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