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New style clinical trials in schizophrenia

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References

  1. Meltzer HY: Clozapine: is another view valid [editorial]? Am J Psychiatry 1995, 152:821–825.

    PubMed  CAS  Google Scholar 

  2. Carpenter WT, Conley RR, Buchanan RW, et al.: Patient response and resource management: another view of clozapine treatment of schizophrenia. Am J Psychiatry 1995, 152:827–832.

    PubMed  Google Scholar 

  3. Carpenter WT, Conley RR, Buchanan RW, et al.: Clozapine conflict [letter to Editor in rebuttal to editorial by Meltzer H, Am J Psychiatry 1995, 152:821-825]. Am J Psych 1996,153:1505–1507.

    Google Scholar 

  4. Tandon R, Goldman R, DeQuardo JR, et al.: Positive and negative symptoms co-vary during clozapine treatment in schizophrenia. J Psychiatric Res 1993, 27:341–347.

    Article  Google Scholar 

  5. Conley R, Richardson C, Kent D, et al.: Clozapine responses varies in deficit vs. non-deficit schizophrenic subjects [abstract]. Biol Psychiatry 1994, 35(9):746.

    Article  Google Scholar 

  6. Lieberman JA, Safferman AZ, Pollack S, et al.: Clinical effects of clozapine in chronic schizophrenia: response to treatment and predictors of outcome. Am J Psychiatry 1994, 151(2):1744–1752.

    PubMed  CAS  Google Scholar 

  7. Buchanan RW, Breier A, Kirkpatrick B, et al.: Positive and negative symptom response to clozapine in schizophrenic patients with and without deficit syndrome. Am J Psychiatry 1998, 155(6):751–760.

    PubMed  CAS  Google Scholar 

  8. Rosenheck R, Dunn L, Peszke M, et al.: Impact of clozapine on negative symptoms and on the deficit syndrome in refractory schizophrenia. Department of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia. Am J Psychiatry 1999, 156(1):88–93.

    PubMed  CAS  Google Scholar 

  9. Schooler N, Marder S, Kane J, et al.: Clozapine and risperidone: a 29-week randomized clinical trial [abstract]. Schizophren Res 1999, 36(1-3):296.

    Google Scholar 

  10. Wahlbeck K, Cheine M, Essali A, Adams C: Evidence of clozapine’s effectiveness in schizophrenia: a systematic review and meta-analysis of randomized trials. Am J Psychiatry 1999, 156(7):990–999.

    PubMed  CAS  Google Scholar 

  11. Carpenter WT: Psychopathology and common sense: where we went wrong with negative symptoms [editorial]. Biol Psychiatry 1991, 29:735–737.

    Article  PubMed  Google Scholar 

  12. Carpenter WT: The deficit syndrome [editorial]. Am J Psychiatry 1994, 151:327–329.

    PubMed  Google Scholar 

  13. Javitt DC, Zylberman I, Zukin SR, et al.: Amelioration of negative symptoms in schizophrenia by glycine. Am J Psychiatry 1994, 151:1234–1236.

    PubMed  CAS  Google Scholar 

  14. Goff DC, Tsai G, Manoach DS, Coyle JT: Dose-finding trial of d-cycloserine added to neuroleptics for negative symptoms in schizophrenia. Am J Psychiatry 1995, 152:1213–1215.

    PubMed  CAS  Google Scholar 

  15. Heresco-Levy U, Javitt DC, Ermilov M, et al.: Double-blind, placebo-controlled, crossover trial of glycine adjuvant therapy for treatment-resistant schizophrenia. Br J Psychiatry 1996, 169:610–617.

    Article  PubMed  CAS  Google Scholar 

  16. Goff DC, Tsai G, Levitt J, et al.: A placebo-controlled trial of D-cycloserine added to conventional neuroleptics in patients with schizophrenia. Arch Gen Psychiatry 1999, 56:21–27.

    Article  PubMed  CAS  Google Scholar 

  17. Heresco-Levy U, Javitt DC, Ermilov M, et al.: Efficacy of highdose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch Gen Psychiatry 1999, 56:29–36.

    Article  PubMed  CAS  Google Scholar 

  18. Tsai G, Yang P, Chung L-C, et al.: D-serine added to antipsychotics for the treatment of schizophrenia. Biol Psychiatry 1998, 44:1081–1089.

    Article  PubMed  CAS  Google Scholar 

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Carpenter, W.T. New style clinical trials in schizophrenia. Curr Psychiatry Rep 1, 11–12 (1999). https://doi.org/10.1007/s11920-999-0004-2

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