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Impact of Postpartum Mental Illness Upon Infant Development

  • Child and Adolescent Disorders (TD Benton, Section Editor)
  • Published:
Current Psychiatry Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

This review evaluates the state of the research regarding the effects of postpartum mental illness on the developing infant. It defines the scope of these disorders in the literature, and includes the impact of disorders referred to as perinatal mood and anxiety disorders (PMADs) on infants.

Recent Findings

New research reveals that PMADs apply to not only mothers, but that fathers can also experience perinatal depression and anxiety. When untreated in a primary caregiver, PMADs adversely affect parental cognitions and beliefs, attachment to the infant, and the growing caregiver-infant relationship. PMADs affect early developmental outcomes of infants including neurosynaptic development, regulatory development, and developmental milestones.

Summary

Early identification and treatment for PMADs are critical to ensure optimal infant development. Standardized and routine screening for PMADs, especially in the first 6 months postpartum, and cross-disciplinary communication among medical providers afford the best opportunity for early identification and treatment.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance

  1. Centers for Disease Control (CDC). Prevalence of self-reported postpartum depressive symptoms—17 states, 200-2005. MMWR Morb Mortal Wkly Rep. 2008;57(14):362–6.

    Google Scholar 

  2. Kuppala VS, Tabangin M, Haberman B, Streichen J, Yolton K. Current state of high-risk infant follow-up care in the United States: results of a national survey of academic follow-up programs. J Perinatol. 2012;32(40):293–8.

    Article  CAS  PubMed  Google Scholar 

  3. Stein A, Le M, Sylva K, Barnes J, Leach P, FCCC Team. The influence of maternal depression, caregiving, and socioeconomic status in the post-natal year on children’s language development. Child Care Health Dev. 2008;34(5):603–12.

    Article  CAS  PubMed  Google Scholar 

  4. Biaggi A, Conroy S, Pawlby S, Pariante CM. Identifying the women at risk of antenatal anxiety and depression: a systematic review. J Affect Disord. 2016;191:62–77.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Holditch-Davis D, Mile MS. Understanding and treating the psychosocial consequences of pregnancy complications and the birth of a high-risk infant. In: Wenzel A, editor. The Oxford handbook of perinatal psychology. New York: Oxford University Press; 2016; Chapter XV: 548–572.

    Google Scholar 

  6. Alici-Evcimen Y, Sudak DM. Postpartum depression. Prim Care Update Ob Gyns. 2003;109(50):210–6.

    Article  Google Scholar 

  7. Glover V. Maternal depression, anxiety and stress during pregnancy and child outcome: what needs to be done. Best Pract Res Clin Obstet Gynaecol. 2014;28:25–35.

    Article  PubMed  Google Scholar 

  8. Alipour Z, Lamyian M, Hajizadeh E. Anxiety and fear of childbirth as predictors of postnatal depression in nulliparous women. Women Birth. 2012;25:e37–43.

    Article  PubMed  Google Scholar 

  9. Goodman JH, Watson GR, Stubbs B. Anxiety disorders in postpartum women: a systematic review and meta-analysis. J Affect Disord. 2016;203:292–331.

    Article  PubMed  Google Scholar 

  10. Sit D, Rothschild AJ, Wisner KL. A review of postpartum psychosis. J Women’s Health. 2006;15(4):352–68.

    Article  Google Scholar 

  11. Zelfkowitz P, Bardin C, Papageorgiou A. Anxiety affects the relationship between parents and their very low birth weight infants. Infant Mental Health J. 2007;28(3):296–313.

    Article  Google Scholar 

  12. Beck CT. The effects of postpartum depression on maternal-infant interaction: a meta-analysis. Nurs Res. 1995;44(5):298–304.

    Article  CAS  PubMed  Google Scholar 

  13. Singley DB, Edwards LM. Men’s perinatal mental health in the transition to fatherhood. Prof Psychol Res Pract. 2015;46(5):309–16.

    Article  Google Scholar 

  14. Paulson JF, Bazemore SD. Prenatal and postpartum depression in fathers and its association with maternal depression: a meta-analysis. J Am Med Assoc. 2010;303(19):1961–9.

    Article  CAS  Google Scholar 

  15. • Paulson JF, Bazemore SD, Goodman JH, Leiferman JA. The course and interrelationship of maternal and paternal perinatal depression. Arch Womens Ment Health. 2016;19(4):655–63. This article examined the course of maternal and paternal postpartum depression from the prenatal period to 6 months postpartum. It found that both maternal and paternal depression were fairly stable across this time period and that paternal depression in the prenatal period was associated with increased severity of maternal depression postnatally.

    Article  PubMed  PubMed Central  Google Scholar 

  16. American College of Obstetricians and Gynecologists. Screening for perinatal depression. Committee Opinion No. 630. Obstet Gynecol. 2015; 125:1268–71. https://www.acog.org/Resources-And-Publications/Committee-Opinions/Committee-on-Obstetric-Practice/Screening-for-Perinatal-Depression#2. Accessed 26 May 2017.

  17. Earls MF. Incorporating recognition and management of perinatal and postpartum depression into pediatric practice. Pediatrics. 2010;126(5):1032–9. https://doi.org/10.1542/peds.2010-2348. (accessed 6/26/17)

    Article  PubMed  Google Scholar 

  18. Tahirkehil N, Cherry AS, Tackett AP, McCaffree MA, Gillaspy SR. Postpartum depression on the neonatal intensive care until: current perspectives. Int J Womens Health. 2014;6:975–9876.

    Google Scholar 

  19. Weaver IC, Cervoni N, Champagne FA, D’Alessio AC, Sharma S, et al. Epigenetic programming by maternal behavior. Nat Neurosci. 2004;7:847–54.

    Article  CAS  PubMed  Google Scholar 

  20. Knudsen EI. Sensitive periods in the development of the brain and behavior. J Cogn Neurosci. 2004;16:1412–25.

    Article  PubMed  Google Scholar 

  21. Greenberg MT, Cmic KA. Longitudinal predictors of developmental status and social interaction in premature and full-term infants at age two. Child Dev. 1988;59:554–70.

    Article  CAS  PubMed  Google Scholar 

  22. National Scientific Council on the Developing Child. The timing and quality of early experiences combine to shape brain architecture: working paper #5. 2007: 1–9. http://www.developingchild.net. Accessed 26 Jun 2017.

  23. Henshaw EJ, Fried R, Teeters JB, Siskind EE. Maternal expectations and postpartum emotional adjustment in first-time mothers: results of a questionnaire survey. J Psychosom Obstet Gynecol. 2015;35(5):69–75.

    Google Scholar 

  24. Webb R, Ayers S. Cognitive biases in processing infant emotion by women with depression, anxiety, and posttraumatic stress disorder in pregnancy or after birth: a systemic review. Cognit Emot. 2015;29(7):1278–94.

    Article  Google Scholar 

  25. O’Mahen HA, Boyd A, Gashe C. Rumination decreases parental problem-solving effectiveness in dysphoric postnatal mothers. J Behav Ther Exp Psychiatry. 2015;47:18–24.

    Article  PubMed  Google Scholar 

  26. Thomason E, Flynn HA, Himle JA, Volling BL. Are women’s parenting-specific beliefs associated with depressive symptoms in the perinatal period? Development of the rigidity of maternal beliefs scale. Depress Anxiety. 2015;32(2):141–8.

    Article  PubMed  Google Scholar 

  27. Tester-Jones M, Karl A, Watkins E, O’Mahen H. Rumination in dysphoric mothers negatively affects mother-infant interactions. J Child Psychol Psychiatry. 2017;58(1):38–45.

    Article  PubMed  Google Scholar 

  28. Ohoka H, Koide T, Goto S, Murase S, Kanai A, et al. Effects of maternal depressive symptomology during pregnancy and the postpartum period on infant-mother attachment. Psychiatry Clin Neurosci. 2014;68(8):631–9.

    Article  PubMed  Google Scholar 

  29. Tester-Jones M, O’Mahen H, Watkins E. The impact of maternal characteristics, infant temperament and contextual factors on maternal responsiveness to infant. Infant Behav Dev. 2015;40:1–11.

    Article  PubMed  Google Scholar 

  30. Sabsavini A, Zavagli V, Guarini A, et al. Dyadic co-regulation, affective intensity and infant’s development at 12 months: a comparison among extremely preterm and full-term dyads. Infant Behav Dev. 2015;40:29–40.

    Article  Google Scholar 

  31. Pinhiero KAT, Pinheiro RT, da Cunha Coelho FM, da Silva RA, Quevedo LA, et al. Serum NGF, BDNF, and IL-6 levels in postpartum mothers as predictors of infant development: the influence of affective disorders. PLoS One. 2014;9(4):1–7.

    Google Scholar 

  32. Lebel C, Walton M, Letourneau N, Giesbrecht GF, Kaplan BJ, Dewey D. Prepartum and postpartum maternal depressive symptoms are related to children’s brain structure in preschool. Biol Psychiatry. 2015;80:859–68.

    Article  PubMed  Google Scholar 

  33. • Sharkey KM, Iko IN, Machan JT. Infant sleep and feeding patterns are associated with maternal sleep, stress, and depressed mood in women with a history of MDD. Arch Womens Health. 2016;19(2):209–18. This article highlights the importance of maternal psychopathology on infant regulatory behaviors.

    Article  Google Scholar 

  34. Silva GAP, Costa KAO, Giugliani ERJ. Infant feeding: beyond the nutritional aspects. J Pediatr. 2016;363:1–6.

    Google Scholar 

  35. Smith-Nielson J, Tharner A, Krogh MT, Vaever MS. Effects of maternal postpartum depression in a well-resourced sample: early concurrent and long-term effects on infant cognitive, language, and motor development. Scand J Psychol. 2016;57(6):571–83.

    Article  Google Scholar 

  36. Kawai E, Takagai S, Takei N, Itoh H, Kanayama N, Tsuchiya KJ. Maternal postpartum depressive symptoms predict delay in non-verbal communication in 14-month-old infants. Infant Behav Dev. 2017;46:33–44.

    Article  PubMed  Google Scholar 

  37. Kim P, Rigo P, Leckman JF, Mayes LC, Cole PM, et al. A prospective longitudinal study of perceived infant outcomes at 18-24 months: neural and psychological correlates of parental thoughts and actions assessed during the first month postpartum. Front Psychol. 2015;6:1–14.

    Google Scholar 

  38. Meiser S, Zietlow AL, Reck C, Trauble B. The impact of postpartum depression and anxiety disorders on children’s processing of facial emotional expressions at pre-school age. Arch Womens Ment Health. 2015;18(5):707–16.

    Article  PubMed  Google Scholar 

  39. Fisher SD, Brock RL, O’Hara MW, Kopelman R, Stuart S. Longitudinal contribution of maternal and paternal depression to toddler behaviors: interparental conflict and later depression as mediators. Couple Fam Psychol Res Pract. 2015;4(2):61–73.

    Article  Google Scholar 

  40. • Sweeney S, MacBeth A. The effects of paternal depression on child and adolescent outcomes: a systematic review. J Affect Disord. 2016;205:44–59. This article provides an up to date review of studies assessing the impact of paternal depression on child outcomes, across childhood from infancy to adolescence. It includes a useful summary table of the studies\ and also a discussion of mechanisms of risk.

    Article  PubMed  Google Scholar 

  41. deCamps MD, Phillipp D, Israel A, Vigod S. Maternal-infant mental health: postpartum group intervention. Arch Womens Ment Health. 2016;19(2):243–51.

    Article  Google Scholar 

  42. Werner EA, Gustafsson HC, Lee S, Feng T, Jiang N. PREPP: postpartum depression prevention through the mother-infant dyad. Arch Womens Ment Health. 2016;19(2):229–42.

    Article  PubMed  Google Scholar 

  43. Cano Gimenez E, Sanchez-Luna M. Providing parents with individualised support in a neonatal intensive care unit reduced stress, anxiety and depression. Acta Paediatr. 2015;104(7):300–5.

    Article  Google Scholar 

  44. Shaw RJ, Bernard RS, DeBlois T, Ikuta LM, Ginzburg K, et al. The relationship between acute stress disorder and posttraumatic stress disorder in the neonatal intensive care unit. Psychosom J Consult Liaison Psychiatry. 2009;50(2):131–7.

    Google Scholar 

  45. Hynan MT, Mounts KO, Vanderbilt DL. Screening parents of high-risk infants for emotional distress: rationale and recommendations. J Perinatol. 2013;33:748–53.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Wanjiku F. M. Njoroge.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Child and Adolescent Disorders

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Hoffman, C., Dunn, D.M. & Njoroge, W.F.M. Impact of Postpartum Mental Illness Upon Infant Development. Curr Psychiatry Rep 19, 100 (2017). https://doi.org/10.1007/s11920-017-0857-8

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  • DOI: https://doi.org/10.1007/s11920-017-0857-8

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