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Current Psychiatry Reports

, 19:83 | Cite as

Depression and Anxiety in Polycystic Ovary Syndrome: Etiology and Treatment

  • Laura G. Cooney
  • Anuja Dokras
Reproductive Psychiatry and Women’s Health (CN Epperson, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Reproductive Psychiatry and Women's Health

Abstract

Purpose of Review

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive age women and is associated with an increased prevalence of depression and anxiety symptoms. This review presents potential mechanisms for this increased risk and outlines treatment options.

Recent Findings

Women with PCOS have increased odds of depressive symptoms (OR 3.78; 95% CI 3.03–4.72) and anxiety symptoms (OR 5.62; 95% CI 3.22–9.80). Obesity, insulin resistance, and elevated androgens may partly contribute to this association. Therefore, in addition to established treatment options, treatment of PCOS-related symptoms with lifestyle modification and/or oral contraceptive pills may be of benefit.

Summary

Screening for anxiety and depression is recommended in women with PCOS at the time of diagnosis. The exact etiology for the increased risk in PCOS is still unclear. Moreover, there is a paucity of published data on the most effective behavioral, pharmacological, or physiological treatment options specifically in women with PCOS.

Keywords

PCOS Depression Anxiety Treatment 

Notes

Compliance with Ethical Standards

Conflict of Interest

Laura G. Cooney and Anuja Dokras declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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© Springer Science+Business Media, LLC 2017

Authors and Affiliations

  1. 1.Department of Obstetrics and GynecologyUniversity of PennsylvaniaPhiladelphiaUSA

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