Abstract
Several psychotherapies have been established as effective treatments for posttraumatic stress disorder (PTSD) including prolonged exposure, cognitive processing therapy, and cognitive therapy for PTSD. Understanding the key mechanisms of these treatments, i.e., how these treatments lead to therapeutic benefits, will enable us to maximize the efficacy, effectiveness, and efficiency of these therapies. This article provides an overview of the theorized mechanisms for each of these treatments, reviews the recent empirical evidence on psychological mechanisms of these treatments, discusses the ongoing debates in the field, and provides recommendations for future research. Few studies to date have examined whether changes in purported treatment mechanisms predict subsequent changes in treatment outcomes. Future clinical trials examining treatments for PTSD should use study designs that enable researchers to establish the temporal precedence of change in treatment mechanisms prior to symptom reduction. Moreover, further research is needed that explores the links between specific treatment components, underlying change mechanisms, and treatment outcomes.
Similar content being viewed by others
Notes
Eye Movement Desensitization and Reprocessing has also been established as an effective treatment for PTSD and is recommended by practice guidelines. To date, no studies have examined the underlying mechanisms of EMDR; rather, research has focused heavily on identifying the importance of specific treatment techniques (i.e., whether bilateral stimulation is a necessary component of treatment). Given that there are no empirical studies on the underlying mechanisms of EMDR, this treatment is not discussed in the current review.
Doss refers to treatment components as “change processes,” therapy techniques as “therapy change processes,” and patient events as “client change processes” in his article. The terms “process” and “mechanism” are often used interchangeably in the psychotherapy literature. Because Doss’ original terms may be confusing for readers, I have modified these terms to more closely reflect the nature of these constructs.
References
Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
American Psychiatric Association Work Group on ASD and PTSD. Practice guideline for the treatment of patients with acute stress disorder and posttraumatic stress disorder. Washington, DC: Author; 2004.
Australian Centre for Posttraumatic Mental Health. Australian guidelines for the treatment of adults with acute stress disorder and posttraumatic stress disorder: Information for people with ASD and PTSD, their families and carers. 2007.
National Institute for Health and Clinical Excellence. Posttraumatic stress disorder (PTSD): The management of PTSD in adults and children in primary and secondary care (NICE Clinical Guideline 26). 2005. Retrieved from http://guidance.nice.org.uk/CG26. Accessed 19 Dec 2014.
Stein DJ, Cloitre M, Nemeroff CB, Nutt DJ, Seedat S, Shalev AY, et al. Cape Town consensus on posttraumatic stress disorder. CNS Spectr. 2009;14(1 Suppl 1):52–8.
Department of Veterans Affairs and Department of Defense. Management of post-traumatic stress. Washington, DC: Department of Veterans Affairs; 2010. Retrieved from http://www.healthquality.va.gov/Post_Traumatic_Stress_Disorder_PTSD.asp.
Foa EB, Keane TM, Friedman MJ, Cohen J. Effective treatments for PTSD: practice guidelines from the International Society for Traumatic Stress Studies. 2nd ed. New York: Guilford Press; 2009.
Foa E, Rothbaum BO. Treating the trauma of rape: cognitive-behavior therapy for PTSD. New York: Guilford Press; 1998.
Foa E, Hembree E, Rothbaum B. Prolonged exposure therapy for PTSD: emotional processing of traumatic experiences, therapist guide. New York: Oxford University Press; 2007.
Resick PA, Schnicke MK. Cognitive processing therapy for sexual assault victims. J Consult Clin Psychol. 1992;60(5):748–56.
Resick PA, Schnicke MK. Cognitive processing therapy for rape victims: a treatment manual. Newbury Park, CA: Sage; 1993.
Resick PA, Nishith P, Weaver TL, Astin MC, Feuer CA. A comparison of cognitive-processing therapy with prolonged exposure and a waiting condition for the treatment of chronic posttraumatic stress disorder in female rape victims. J Consult Clin Psychol. 2002;70(4):867–79.
Ehlers A, Clark DM. A cognitive model of posttraumatic stress disorder. Behav Res Ther. 2000;38(4):319–45.
Ehlers A, Clark DM, Hackmann A, Grey N, Liness S, Wild J, et al. Intensive cognitive therapy for PTSD: a feasibility study. Behav Cogn Psychother. 2010;38(4):383–98.
Ehlers A, Clark DM, Hackmann A, McManus F, Fennell M, Herbert C, et al. A randomized controlled trial of cognitive therapy, self-help booklet, and repeated early assessment as early interventions for posttraumatic stress disorder. Arch Gen Psychiatry. 2003;60(10):1024–32.
Ehlers A, Clark DM, Hackmann A, McManus F, Fennell M. Cognitive therapy for post-traumatic stress disorder: development and evaluation. Behav Res Ther. 2005;43(4):413–31.
Watts BV, Schnurr PP, Mayo L, Young-Xu Y, Weeks WB, Friedman MJ. Meta-analysis of the efficacy of treatments for posttraumatic stress disorder. J Clin Psychiatry. 2013;74(6):e541–50.
Bradley R, Greene J, Russ E, Dutra L, Westen D. A multidimensional meta-analysis of psychotherapy for PTSD. Am J Psychiatry. 2005;162(2):214–27.
Tuerk PW, Yoder M, Grubaugh A, Myrick H, Hamner M, Acierno R. Prolonged exposure therapy for combat-related posttraumatic stress disorder: an examination of treatment effectiveness for veterans of the wars in Afghanistan and Iraq. J Anxiety Disord. 2011;25(3):397–403.
Schulz PM, Resick PA, Huber LC, Griffin MG. The effectiveness of cognitive processing therapy for PTSD with refugees in a community setting. Cogn Behav Pract. 2006;13(4):322–31.
Doss BD. Changing the way we study change in psychotherapy. Clin Psychol (New York). 2004;11(4):368–86.
Foa EB, Kozak MJ. Treatment of anxiety disorders: implications for psychopathology. In: Tuma EH, Maser JD, editors. Anxiety and the anxiety disorders. Hillsdale: Laurance Erlbaum Associates; 1985. p. 421–52.
Foa EB, Kozak MJ. Emotional processing of fear: exposure to corrective information. Psychol Bull. 1986;99(1):20–35.
Zalta AK, Foa EB. Exposure therapy: promoting emotional processing of pathological anxiety. In: O’Donohue W, Fisher JE, editors. Cognitive behavior therapy: core principles for practice. Hoboken: Wiley; 2012. p. 75–104.
Foa EB, Ehlers A, Clark DM, Tolin DG, Orsillo SM. The posttraumatic cognitions inventory (PTCI): development and validation. Psychol Assess. 1999;11(3):303–14.
Kleim B, Grey N, Wild J, Nussbeck FW, Stott R, Hackmann A, et al. Cognitive change predicts symptom reduction with cognitive therapy for posttraumatic stress disorder. J Consult Clin Psychol. 2013;81(3):383–93. In this effectiveness study of cognitive therapy for PTSD, session-to-session reductions in PTSD predicted subsequent reductions in PTSD symptoms.
Ehlers A. Trauma-focused cognitive behavior therapy for posttraumatic stress disorder and acute stress disorder. In: Simos G, Hofmann SG, editors. CBT for anxiety disorders: a practitioner book. West Sussex, UK: Wiley-Blackwell; 2013. p. 161–89.
Sobel AA, Resick PA, Rabalais AE. The effect of cognitive processing therapy on cognitions: impact statement coding. J Trauma. 2009;22(3):205–11.
Vogt DS, Shipherd JC, Resick PA. Posttraumatic maladaptive beliefs scale: evolution of the personal beliefs and reactions scale. Assessment. 2012;19(3):308–17.
Zalta A, Gillihan S, Fisher A, Mintz J, McLean C, Yehuda R, et al. Change in negative cognitions associated with PTSD predicts symptom reduction in prolonged exposure. J Consult Clin Psychol. 2014;82(1):171–5. In this study of prolonged exposure, session-to- session reductions in PTSD related cognitions predicted subsequent reductions in PTSD symptoms.
Gilman R, Schumm JA, Chard KM. Hope as a change mechanism in the treatment of posttraumatic stress disorder. Psychol Trauma. 2012;4(3):270–7.
Snyder CR, Harris C, Anderson JR, Holleran S, Irving LM, Gibb J, et al. The will and the ways: development and validation of an individual differences measure of hope. J Pers Soc Psychol. 1991;60(4):570–85.
Gallagher MW, Resick PA. Mechanisms of change in cognitive processing therapy and prolonged exposure therapy for PTSD: preliminary evidence for the differential effects of hopelessness and habituation. Cognitive Ther Res. 2012;36(6):750–5. This study showed that cognitive processing therapy led to greater reductions in hopelessness than prolonged exposure and reductions in hopelessness mediated the relationship between treatment type and treatment outcome.
Bluett EJ, Zoellner LA, Feeny NC. Does change in distress matter? Mechanisms of change in prolonged exposure for PTSD. J Behav Ther Exp Psy. 2014;45(1):97–104. This study showed that patients receiving prolonged exposure who did not demonstrate reliable changes in distress during imaginal exposure from pre to post treatment still showed marked improvement in PTSD symptom severity.
Luborsky L, Singer B, Luborsky L. Comparative studies of psychotherapies: is it true that "everyone has one and all must have prizes"? Arch Gen Psychiatry. 1975;32(8):995–1008.
DeRubeis RJ, Brotman MA, Gibbons CJ. A conceptual and methodological analysis of the nonspecifics argument. Clin Psychol-Sci Pr. 2005;12(2):174–83.
Mausbach BT, Moore R, Roesch S, Cardenas V, Patterson TL. The relationship between homework compliance and therapy outcomes: an updated meta-analysis. Cognit Ther Res. 2010;34(5):429–38.
Huppert JD, Ledley DR, Foa EB. The use of homework in behavior therapy for anxiety disorders. J Psychother Integr. 2006;16(2):128–39.
Insel T. NIMH’s new focus in clinical trials. National Institute of Mental Health. 2013. http://www.nimh.nih.gov/funding/grant-writing-and-application-process/concept-clearances/2013/nimhs-new-focus-in-clinical-trials.shtml. Accessed 19 Dec 2014.
Insel T. Director’s blog: a new approach to clinical trials. National Institute of Mental Health. 2014. http://www.nimh.nih.gov/about/director/2014/a-new-approach-to-clinical-trials.shtml. Accessed 19 Dec 2014.
Acknowledgments
The author would like to thank Nicole Heath and Rebecca Blais for the feedback on a draft of this manuscript.
Compliance with Ethics Guidelines
ᅟ
Conflict of Interest
Alyson K. Zalta receives grant support from NIH (K23 MH103394).
Human and Animal Rights and Informed Consent
This article does not contain any studies with human or animal subjects performed by any of the authors.
Author information
Authors and Affiliations
Corresponding author
Additional information
This article is part of the Topical Collection on Disaster Psychiatry: Trauma, PTSD, and Related Disorders
Rights and permissions
About this article
Cite this article
Zalta, A.K. Psychological Mechanisms of Effective Cognitive–Behavioral Treatments for PTSD. Curr Psychiatry Rep 17, 23 (2015). https://doi.org/10.1007/s11920-015-0560-6
Published:
DOI: https://doi.org/10.1007/s11920-015-0560-6