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Maximizing treatment outcome in post-traumatic stress disorder by combining psychotherapy with pharmacotherapy

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Abstract

There are no systematic data available on combining medication and psychotherapy in the treatment of individuals with post-traumatic stress disorder (PTSD), despite its widespread practice. Careful review of the acute trials literature reveals that psychosocial and pharmacologic treatments each leave a substantial proportion of individuals with residual symptoms. This paper discusses a treatment model involving a phaseoriented treatment approach that begins with pharmacotherapy and continues with trauma-focused psychotherapy. Other combined approaches also are discussed. A rationale supporting the need for psychosocial treatment in the majority of patients who receive pharmacotherapy for chronic PTSD is presented.

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Marshall, R.D., Cloitre, M. Maximizing treatment outcome in post-traumatic stress disorder by combining psychotherapy with pharmacotherapy. Curr Psychiatry Rep 2, 335–340 (2000). https://doi.org/10.1007/s11920-000-0078-3

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