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Ultrasound-Guided Peripheral Nerve Blocks: A Practical Review for Acute Cancer-Related Pain

  • Alternative Treatments for Pain Medicine (M Jones, Section Editor)
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Abstract

Purpose of Review

Ultrasound-guided regional techniques, including catheter-based approaches, are a subset of interventional therapies that have gained interest as an option for managing acute cancer-related pain. The authors sought to review the available published evidence and to discuss practical recommendations for expanding access to such therapies.

Recent Findings

In a MEDLINE/Pubmed search of ultrasound-guided peripheral nerve blocks and peripheral nerve catheters for specific anatomic targets, a total of 28 case reports and case series were identified. Included studies described improved analgesia and reduced opioid requirements with highly variable duration of effect. Current level of evidence remains limited.

Summary

Pain is a symptom that markedly impacts the quality of life of cancer patients and ultrasound-guided regional techniques are a promising therapeutic option albeit with a limited evidence base. Practical recommendations offered for coordinating access to such therapies in the inpatient, emergency department, and outpatient settings may expand interest and facilitate higher quality research.

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Authors and Affiliations

  1. Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

    David Hao & Michael Fiore

  2. Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

    Christopher Di Capua

  3. Department of Anesthesia and Critical Care, Memorial Sloan Kettering Cancer Center, New York, USA

    Amitabh Gulati

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Correspondence to David Hao.

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Dr. Amitabh Gulati is a consultant for Medtronic, Flowonix, SPR Medical, Nalu Medical and an advisor for Spark Medical and AIS Healthcare. The other authors certify that he or she, or a member of his or her immediate family, has no commercial association (i.e., consultancies, stock ownership, equity interest, patent/licensing arrangements) that might pose a conflict of interest in connection with the submitted manuscript.

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Hao, D., Fiore, M., Di Capua, C. et al. Ultrasound-Guided Peripheral Nerve Blocks: A Practical Review for Acute Cancer-Related Pain. Curr Pain Headache Rep 26, 813–820 (2022). https://doi.org/10.1007/s11916-022-01089-9

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