Cancer and Referred Facial Pain

Abstract

Orofacial pain may be a symptom of diverse types of cancers as a result of local or distant tumor effects. The pain can be presented with the same characteristics as any other orofacial pain disorder, and this should be recognized by the clinician. Orofacial pain also can arise as a consequence of cancer therapy. In the present article, we review the mechanisms of cancer-associated facial pain, its clinical presentation, and cancer therapy associated with orofacial pain.

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Acknowledgments

We would like to thank Dr. Joan Phelan, professor and chair of the Oral and Maxillofacial Pathology, Radiology and Medicine at NYU College of Dentistry for the picture of the adenoid cystic carcinoma of minor salivary gland origin.

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Conflict of Interest

Marcela Romero Reyes, Antonia Teruel, and Yi Ye each declare no potential conflicts of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Correspondence to Marcela Romero-Reyes.

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This article is part of the Topical Collection on Secondary Headache

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Romero-Reyes, M., Teruel, A. & Ye, Y. Cancer and Referred Facial Pain. Curr Pain Headache Rep 19, 37 (2015). https://doi.org/10.1007/s11916-015-0512-1

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Keywords

  • Pain
  • Orofacial
  • Facial
  • Cancer