Migraine is commonly associated with nausea and vomiting, though, interestingly, vomiting has also been reported by some patients to be therapeutic, and may actually stop a migraine attack. In this review, we will first discuss the epidemiology of nausea and vomiting in migraine. Further, we will briefly review the connections between the enteric nervous system, the autonomic nervous system, and the central nervous system as they pertain to understanding the question of “Why does vomiting stop a migraine attack?”
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We would like to thank the following for their insightful comments and contributions to our survey questions: Dr Allan Purdy (Dalhousie University, Nova Scotia); Dr.David Kudrow (California Medical Clinic for Headache); Dr Emeran Mayer (UCLA); Dr Massimo Leone (Istituto Nazionale Neurologico C. Besta, Milano, Italy); Dr Peter Goadsby (UCSF); and Dr K Ravishankar (Jaslok Hospital and Research Centre and Lilavati Hospital and Research Centre, Mumbai, India).
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Conflict of Interest
Nu Cindy Chai reported no potential conflicts of interest relevant to this article.
Dr Robert E. Shapiro reported no potential conflicts of interest relevant to this article.
Dr Alan M. Rapoport reported no potential conflicts of interest relevant to this article.
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This article does not contain any studies with human or animal subjects performed by any of the authors.
This article is part of the Topical Collection on Migraine
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Chai, N.C., Shapiro, R.E. & Rapoport, A.M. Why Does Vomiting Stop a Migraine Attack?. Curr Pain Headache Rep 17, 362 (2013). https://doi.org/10.1007/s11916-013-0362-7