Skip to main content

Advertisement

Log in

Migraine-Related Symptoms in Childhood

  • Childhood and Adolescent Headache (S Evers, Section Editor)
  • Published:
Current Pain and Headache Reports Aims and scope Submit manuscript

Abstract

Periodic disorders of childhood often represent precursors of migraine. As we advance our knowledge of migraine and its complicated phenotypic presentation in childhood, we have noted the similarities in overlapping symptoms of children presenting with childhood periodic syndromes. There is often a positive family history of migraine in children that present with periodic syndromes. There is a known transformation of periodic syndromes from childhood into adult migraine with and without aura phenotype. There has been an evolution of our understanding of what was initially referred to as periodic symptoms of childhood and more recently been called childhood periodic syndromes and is now evolving into the terminology of episodic symptoms that are associated with migraine. International classification of headache disorders has been instrumental in the evolution of the classification of headache and children adults. The most recent classification utilizes and replaces the periodic symptom terminology with episodic symptoms that will no longer be limited to just childhood. This article will address the evolution of our understanding of the diagnostic criteria, pathophysiology and management of the episodic syndromes that may be associated with migraine.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. Lanzi G, Zambrino CA, Balottin U, Tagliasacchi M, Vercelli P, Termine C. Periodic syndrome and migraine in children and adolescents. Ital J Neurol Sci. 1997;18:283–8.

    Article  PubMed  CAS  Google Scholar 

  2. Winner P. Childhood periodic syndromes and migraine. Curr Pain Head Rep. 2005;9:197–201.

    Article  Google Scholar 

  3. Lewis DW, Bigal ME, Winner P. Migraine and the childhood periodic syndromes. In: Winner P, Lewis DW, Rothner AD, editors. Headache in children and adolescence. 2nd ed. Ontario: B.C. Decker; 2008. p. 37–55.

    Google Scholar 

  4. • Lin YP, Ni YH, Weng WC, Lee WT. Cyclic vomiting syndrome and migraine in children. J Formos Med Assoc. 2011;110(6):382–7. Excellent detailed clinical discussion with practical diagnostic information.

    Article  PubMed  Google Scholar 

  5. •• Cuvellier JC, Lepine A. Childhood periodic syndromes. Pediatr Neurol. 2010;42:1–11. Review article with up-to-date pathophysiology and detailed practical treatment options.

    Article  PubMed  Google Scholar 

  6. Li BUK. Cyclic vomiting syndrome: the evolution of understanding of a brain-gut disorder. Adv Pediatr. 2000;47:1–44.

    Google Scholar 

  7. Li BU, Misiewicz L. Cyclic vomiting syndrome: a brain-gut disorder. Gastroenterol Clin North Am. 2003;32:997–1019.

    Article  PubMed  CAS  Google Scholar 

  8. Prakash C, Staiano A, Rothbaum RJ, Clouse RE. Similarities in cyclic vomiting syndrome across age groups. Gastroenterology. 2001;96:684–8.

    CAS  Google Scholar 

  9. Abell TL, Adams KA, Boles RG, et al. Cyclic vomiting syndrome in adults. Neurogastroenterol Motil. 2008;20:269–84.

    Article  PubMed  CAS  Google Scholar 

  10. Li BU, Lefevre F, Chelimsky GG, et al. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition consensus statement on the diagnosis and management of cyclic vomiting syndrome. J Pediatr Gastroenterol Nutr. 2008;47:379–93.

    Article  PubMed  CAS  Google Scholar 

  11. Abu-Arafeh I, Russell G. Prevalence and clinical features of abdominal migraine compared with those of migraine headache. Arch Dis Child. 1995;72:413–7.

    Article  PubMed  CAS  Google Scholar 

  12. Mortimer MJ, Kay J, Jaron A. Clinical epidemiology of childhood abdominal migraine in an urban general practice. Dev Med Child Neurol. 1993;35:243–8.

    Article  PubMed  CAS  Google Scholar 

  13. • Kabbouche MA. Childhood periodic syndromes. In: Hershey AD, Powers SW, Winner P, Kabbouche MA, editors. Pediatric headaches in clinical practice. NJ, USA: Wiley-Blackwell; 2009. p. 101–16. Easy-to-follow comprehensive review of the childhood periodic syndromes.

    Google Scholar 

  14. Dignan F, Abu-Arafeh I, Russell G. The prognosis of childhood abdominal migraine. Arch Dis Child. 2001;84:415–8.

    Article  PubMed  CAS  Google Scholar 

  15. Russell G, Abu-Arafeh I, Symon DN. Abdominal migraine: evidence for existence and treatment options. Paediatr Drugs. 2002;4:1–8.

    PubMed  Google Scholar 

  16. Symon DN, Russell G. Double blind placebo controlled trial of pizotifen syrup in the treatment of abdominal migraine. Arch Dis Child. 1995;72:48–50.

    Article  PubMed  CAS  Google Scholar 

  17. Worawattanakul M, Rhoads JM, Lichtman SN, Ulshen MH. Abdominal migraine: prophylactic treatment and follow-up. J Pediatr Gastroeneterol Nutr. 1999;28:37–40.

    Article  CAS  Google Scholar 

  18. Lundberg PO. Abdominal migraine—diagnosis and therapy. Headache. 1975;15:122–5.

    Article  PubMed  CAS  Google Scholar 

  19. Tan V, Sahami AR, Peebles R, Shaw RJ. Abdominal migraine and treatment with intravenous valproic acid. Psychosomatics. 2006;47:353–5.

    Article  PubMed  Google Scholar 

  20. Perez Plasencia D, Beltran Mateos LD, del Canizo Alvarez A, Sancipriano JA, Calvo Boizas E, Benito Gonzalez JJ. Benign paroxysmal vertigo in childhood. Acta Otorrinolaringol Esp. 1998;49:151–5.

    PubMed  CAS  Google Scholar 

  21. Giffin NJ, Benton S, Goadsby PJ. Benign paroxysmal torticollis of infancy: four new cases and linkage to CACNA1A mutation. Dev Med Child Neurol. 2002;44:490–3.

    Article  PubMed  CAS  Google Scholar 

  22. John B, Klemm E, Haverkamp F. Evidence for altered basal ganglia and cortical functions in transient idiopathic dystonia. J Child Neurol. 2000;15:820–2.

    Article  PubMed  CAS  Google Scholar 

  23. Headache Classification Committee (2013). The international classification of headache disorders, cranial neuralgia and facial pain, 3rd ed. Cephalalgia in Press.

Download references

Conflict of Interest

Dr. Paul Winner reported no potential conflicts of interest relevant to this article.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Paul Winner.

Additional information

This article is part of the Topical Collection on Childhood and Adolescent Headache

Rights and permissions

Reprints and permissions

About this article

Cite this article

Winner, P. Migraine-Related Symptoms in Childhood. Curr Pain Headache Rep 17, 339 (2013). https://doi.org/10.1007/s11916-013-0339-6

Download citation

  • Published:

  • DOI: https://doi.org/10.1007/s11916-013-0339-6

Keywords

Navigation