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Headache and Sleep in Children

  • Childhood and Adolescent Headache (S Evers, Section Editor)
  • Published:
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Abstract

Several scientific studies report a close relationship between sleep and headache: sleep changes may reflect the onset and increase of both duration and frequency of headache attacks. Variations in sleep architecture, together with a poor sleep hygiene in children, may indeed be responsible for the onset of headache and its development into a chronic disease. For a correct clinical management of children with headache, it is therefore fundamental to investigate their sleep habits, architecture and potential disturbances, in order to develop adequate therapeutic plans for both sleep and headache.

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References

Papers of particular interest have been highlighted as: • Of importance •• Of major importance

  1. Abu-Arefeh I, Russell G. Prevalence of headache and migraine in schoolchildren. BMJ. 1994;309:765–9.

    Article  PubMed  CAS  Google Scholar 

  2. Owens JA, Whitmans M. Sleep problems. Curr Probl Pediatr Adolesc Health Care. 2004;34:154–7.

    Article  PubMed  Google Scholar 

  3. Alberti A. Headache and sleep. Sleep Med Rev. 2006;10:431–7.

    Article  PubMed  Google Scholar 

  4. Kelman L, Rains JC. Headache and sleep: examination of sleep patterns and complaint in a large clinical sample of migraineurs. Headache. 2005;45:904–10.

    Article  PubMed  Google Scholar 

  5. Dexter JD, Weitzman ED. The relationship of nocturnal headaches to sleep stage patterns. Neurology. 1970;20:513–8.

    Article  PubMed  CAS  Google Scholar 

  6. Dexter JD. The relationship between stage III and IV and REM sleep and arousals with migraine. Headache. 1979;19:364–9.

    Article  PubMed  CAS  Google Scholar 

  7. Kayed K, Sjaastad O. Nocturnal and early morning headaches. Ann Clin Res. 1985;17:243–6.

    PubMed  CAS  Google Scholar 

  8. Pfaffenrath V, Pollmann W, Ruther E, Lund R, Hajak G. Onset of nocturnal attacks of chronic cluster headache in relation to sleep stages. Acta Neurol Scand. 1986;73:403–7.

    Article  PubMed  CAS  Google Scholar 

  9. Sahota PK, Dexter JD. Sleep and Headache Syndromes: A Clinical Review. Headache. 1990;30:80–4.

    Article  PubMed  CAS  Google Scholar 

  10. Jennum P, Jensen R. Sleep and headache. Sleep Med Rev. 2002;6:471–9.

    Article  PubMed  Google Scholar 

  11. Hill W. On some causes of backwardness and stupidity in children. BMJ. 1889;2:711–2.

    Article  PubMed  CAS  Google Scholar 

  12. Wilkinson M, Williams K, Leyton M. Observations on the treatment of an acute attack of migraine. Res Clin Stud Headache Basel, Karger. 1978;6:141–6.

    CAS  Google Scholar 

  13. Blau JN. Resolution of migraine attacks: Sleep and the recovery phase. J Neurol Neurosurg Psychiatry. 1982;45:223–6.

    Article  PubMed  CAS  Google Scholar 

  14. Dexter JD. Relationship Between Sleep and Headache Syndromes. In: Thorpy MJ, editor. Handbook of sleep disorders. Marcel Dekker: New York; 1990. p. 663–71.

    Google Scholar 

  15. Inamorato E, Minatti Hannuch SN, Zukerman E. The role of sleep in migraine attacks. Arq Neuropsiquiatr. 1993;51:429–32.

    Article  PubMed  CAS  Google Scholar 

  16. •• Bruni O, Fabrizi P, Ottaviano S, et al. Prevalence of sleep disorders in childhood and adolescence with headache: a casecontrol study. Cephalalgia. 1997;17:492–8. This article confirmed, with valid statistical results, a strong association between migraine or headache and different sleep disorders.

    Article  PubMed  CAS  Google Scholar 

  17. Miller VA, Palermo TM, Powers SW, et al. Migraine headaches and sleep disturbances in children. Headache. 2003;43:362–8.

    Article  PubMed  CAS  Google Scholar 

  18. Barabas G, Ferrari M, Matthews WS. Childhood migraine and somnambulism. Neurology. 1983;33:948–9.

    Article  PubMed  CAS  Google Scholar 

  19. Pradalier A, Guittard M, Dry J. Somnambulism, migraine and propranolol. Headache. 1987;27:143–5.

    Article  PubMed  CAS  Google Scholar 

  20. Giroud M, D’Athis P, Guard O, Dumas R. Migraine et somnambulisme Une enquete portant sur 122 migraineux. Rev Neurol. 1986;142:42–6.

    PubMed  CAS  Google Scholar 

  21. Dexter JD. The relationship between disorders of arousal from sleep and migraine. Headache. 1986;26:322.

    Article  Google Scholar 

  22. Paiva T, Batista A, Martins P, Martins A. The relationship between headaches and sleep disturbances. Headache. 1995;35:590–6.

    Article  PubMed  CAS  Google Scholar 

  23. Bille BS. Migraine in school children. A study of the incidence and short-term prognosis, and a clinical, psychological and electroencephalographic comparison between children with migraine and matched controls. Acta Paediatr Suppl. 1962;136:1–151.

    PubMed  CAS  Google Scholar 

  24. Fearon P, Hotopf M. Relation between headache in childhood and physical and psychiatric symptoms in adulthood: National birth cohort study. BMJ. 2001;322:1145.

    Article  PubMed  CAS  Google Scholar 

  25. Rhee H. Relationships between physical symptoms and pubertal development. J Pediatr Health Care. 2005;19:95–103.

    PubMed  Google Scholar 

  26. Pakalnis A, Splaingard M, Splaingard D, Kring D, Colvin A. Serotonin effects on sleep and emotional disorders in adolescent migraine. Headache. 2009;49(10):1486–92.

    Article  PubMed  Google Scholar 

  27. Martin J, Hiscock H, Hardy P, Davey B, Wake M. Adverse associations of infant and child sleep problems and parent health: an Australian population study. Pediatrics. 2007;119:947–55.

    Article  PubMed  Google Scholar 

  28. Owens JA. Epidemiology of sleep disorders during childhood. In: Sheldon SH, Ferber R, Kryger MH, editors. Principles and Practices of Pediatric Sleep Medicine. Philadelphia, PA: Elsevier Saunders; 2005. p. 27–33.

    Chapter  Google Scholar 

  29. Mindell JA, Owens JA. A clinical guide to pediatric sleep: diagnosis and management of sleep problems. Philadelphia, PA: Lippincott Williams Wilkins; 2003.

    Google Scholar 

  30. Mathew NT, Glaze D, Frost JJR. Sleep apnea and other sleep abnormalities in primary headache disorders. In: Rose C, editor. Migraine, Proc 5th Int Migraine Symp. London: Karger; 1985. p. 40–9.

    Google Scholar 

  31. Palayew MD, Kryger MH. Sleep apnea and headache. Headache Quarterly. 1994;5:227–30.

    Google Scholar 

  32. De Giorgis G, Miletto R, Iannuccelli M, Camuffo M, Scerni S. Headache in association with sleep disorders in children: a psychodiagnostic evaluation and controlled clinical study—L-5-HTP versus placebo. Drugs Exp Clin Res. 1987;13:425–33.

    PubMed  Google Scholar 

  33. Smeyers P. Headaches in childhood: association with sleep disorders and psychological implications. Rev Neurol. 1999;28:S150–155.

    PubMed  Google Scholar 

  34. Carotenuto M, Guidetti V, Ruju F, Galli F, Tagliente FR, Pascotto A. Headache disorders as risk factors for sleep disturbances in school aged children. J Headache Pain. 2005;6:268–70.

    Article  PubMed  Google Scholar 

  35. Luc ME, Gupta A, Birnberg JM, Reddick D, Kohrman MH. Characterization of symptoms of sleep disorders in children with headache. Pediatr Neurol. 2006;34:7–12.

    Article  PubMed  Google Scholar 

  36. • Heng K, Wirrell E. Sleep disturbance in children with migraine. J Child Neurol. 2006;21:761–6. This recent study showed the relationship between headache and sleep disorder. Furthermore, it demonstrated that children with migraine are prone to greater sleep and behavioral disturbances than children without headache; in this view, sleep disorders should be routinely queried and give appropriate advice on sleep hygiene.

    Article  PubMed  Google Scholar 

  37. Balottin U, Termine C, Nicoli F, Quadrelli M, Ferrari-Ginevra O, Lanzi G. Idiopathic headache in children under six years of age: a follow-up study. Headache. 2005;45(6):705–15.

    Article  PubMed  Google Scholar 

  38. Guidetti V, Galli F, Fabrizi P, Giannantoni A, Napoli L, Bruni O, et al. Headache and psychiatric comorbidity: clinical aspects and outcome in an 8th years follow-up study. Cephalalgia. 1998;18:455–62.

    Article  PubMed  CAS  Google Scholar 

  39. Katerji MA, Painter MJ. Infantile migraine presenting as colic. J Child Neurol. 1994;9(3):336–7.

    Article  PubMed  CAS  Google Scholar 

  40. Weissbluth M. Colic. In: Ferber R, Kryger M, editors. Principles and Practice of Sleep Medicine in the Child. WB Saunders: Philadelphia; 1995. p. 75–8.

    Google Scholar 

  41. Guidetti V, Ottaviano S, Pagliarini M. Childhood headache risk: warning signs and symptoms present during the first six months of life. Cephalalgia. 1984;4:237–42.

    Article  Google Scholar 

  42. Del Bene E. Multiple aspects of headache risk in children. Adv Neurol. 1982;33:187–98.

    PubMed  Google Scholar 

  43. Lanzi G, Zambrino CA, Balottin U, Tagliasacchi M, Vercelli P, Termine C. Periodic syndrome and migraine in children and adolescents. Ital J Neurol Sci. 1997;18(5):283–8.

    Article  PubMed  CAS  Google Scholar 

  44. Carvalho Dde S, Zukerman E, Hanuch SN, Levyman C, Lima JG. Risk factors in headache in children from 7 to 15. Arq Neuropsiquiatr. 1987;45(4):371–8.

    Article  PubMed  Google Scholar 

  45. Elser JM, Woody RC. Migraine headache in the infant and young child. Headache. 1990;30:366–8.

    Article  PubMed  CAS  Google Scholar 

  46. Hiscock H, Davey MJ. Sleep disorders in infants and children. J Paediatr Child Health. 2012. doi:10.1111/jpc.12033 [Epub ahead of print].

    Google Scholar 

  47. Iglowstien I, Jenni O, Molinari L, Largo M. Sleep duration from infancy to adolescence: reference values and generational trends. Pediatrics. 2003;111:302–7.

    Article  Google Scholar 

  48. Fox AW, Davis RL. Migraine chronobiology. Headache. 1998;38:436–41.

    Article  PubMed  CAS  Google Scholar 

  49. Zurak N. Role of the suprachiasmatic nucleus in the pathogenesis of migraine attacks. Cephalalgia. 1997;17:223–8.

    Article  Google Scholar 

  50. Leone M, Lucini V, D’Amico D. Twenty-four hour melatonin and cortisol plasma levels in relation to timing of cluster headache. Cephalalgia. 1995;15:224–9.

    Article  PubMed  CAS  Google Scholar 

  51. Russo PM, Bruni O, Lucidi F, Ferri R, Violani C. Sleep habits and circadian preference in Italian children and adolescents. J Sleep Res. 2007;16(2):163–9.

    Article  PubMed  Google Scholar 

  52. Bruni O, Russo PM, Ferri R, Novelli L, Galli F, Guidetti V. Relationships between headache and sleep in a non-clinical population of children and adolescents. Sleep Med. 2008;9:542–8.

    Article  PubMed  CAS  Google Scholar 

  53. Wittmann M, Dinich J, Merrow M, Roenneberg T. Social jetlag: misalignment of biological and social time. Chronobiol Int. 2006;23:497–509.

    Article  PubMed  Google Scholar 

  54. Guidetti V, Bruni O, Violani C, Casiello B, Devoto A, Galli F. Sleep wake cycle variations in migrainous children. Cephalalgia. 1999;19:278. abst.

    Google Scholar 

  55. • Bursztein C, Steinberg T, Sadeh A. Sleep, sleepiness, and behavior problems in children with headache. J Child Neurol. 2006;21:1012–9. This study is one of the few actigraphic studies, and it shows the importance of assessing sleep, daytime sleepiness, and psychological adjustment in children complaining about headaches as an integral part of their routine assessment.

    Article  PubMed  Google Scholar 

  56. Guidetti V, Bruni O, Canitano R, Romoli M, Napoli L. Migraine and headache in childhood: sleep disorders and sleep organization. Cephalalgia. 1995;S16:10–2. abst.

    Google Scholar 

  57. Guilleminault C, Eldridge FL, Simmons FB, Dement WC. Sleep apnea in eight children. Pediatrics. 1976;58:23–30.

    PubMed  CAS  Google Scholar 

  58. Chervin RD, Dillon JE, Bassetti C, Ganoczy DA, Pituch KJ. Symptoms of sleep disorders, inattention, and hyperactivity in children. Sleep. 1997;20(12):1185–92.

    PubMed  CAS  Google Scholar 

  59. Bruni O, Novelli L, Guidetti V, Ferri R. Sleep and headache during adolescence. Adolesc Med. 2010;21:446–56.

    Google Scholar 

  60. Mindell JA, Meltzer LJ. Behavioural sleep disorders in children and adolescents. Ann Acad Med. 2008;37:722–8.

    Google Scholar 

  61. •• Bruni O, Galli F, Guidetti V. Sleep hygiene and migraine in children and adolescents. Cephalalgia. 1999;19(S25):58–60. This article offers an alternative approach to the treatment of migraine, introducing a simple modification of sleep behavior without recurring to pharmacological treatment.

    Google Scholar 

  62. Feikema WJ. Headache and chronic sleep deprivation: an often missed relationship in children and also in adults. Ned Tijdschr Geneeskd. 1999;143(38):1897–900.

    PubMed  CAS  Google Scholar 

  63. Gans M. Treating migraine by sleep rationing. J Nerv Ment Dis. 1951;113:405–29.

    PubMed  CAS  Google Scholar 

  64. Peroutka SJ. Dopamine and migraine. Neurology. 1997;49:650–6.

    Article  PubMed  CAS  Google Scholar 

  65. Mascia A, Afra J, Schoenen J. Dopamine and migraine: a review of pharmaceutical, biochemical, neurophysiological and therapeutic data. Cephalalgia. 1998;18:174–82.

    Article  PubMed  CAS  Google Scholar 

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Conflict of interest

Dr. Benedetta Bellini reported no conflicts of interest relevant to this article.

Dr. Sara Panunzi reported no conflicts of interest relevant to this article.

Dr. Oliviero Bruni reported no conflicts of interest relevant to this article.

Dr. Vincenzo Guidetti reported no conflicts of interest relevant to this article.

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Authors and Affiliations

  1. Department of Pediatrics and Child and Adolescent Neuropsychiatry, Faculty of Medicine and Odontoiatry, University “La Sapienza”, Via dei Sabelli n°108, 00185, Rome, Italy

    Benedetta Bellini, Sara Panunzi & Vincenzo Guidetti

  2. Department of Social and Developmental Psychology, Faculty of Medicine and Psychology, University “La Sapienza”, Rome, Italy

    Oliviero Bruni

Authors
  1. Benedetta Bellini
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  2. Sara Panunzi
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  3. Oliviero Bruni
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  4. Vincenzo Guidetti
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Correspondence to Benedetta Bellini.

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This article is part of the Topical Collection on Childhood and Adolescent Headache

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Bellini, B., Panunzi, S., Bruni, O. et al. Headache and Sleep in Children. Curr Pain Headache Rep 17, 335 (2013). https://doi.org/10.1007/s11916-013-0335-x

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