Current Pain and Headache Reports

, Volume 14, Issue 4, pp 261–267 | Cite as

The Role of Chemical Neurolysis in Cancer Pain

  • Dhanalakshmi Koyyalagunta
  • Allen W. Burton


Pain continues to be a significant symptom burden in cancer patients, with prevalence in 53% of patients at all stages of cancer and as high as 58% to 69% in those with advanced cancer. Neurolytic blocks are a mainstay in the armamentarium of cancer pain management, more so in intractable pain from advanced cancer. There is no clear consensus on patient selection, technique, or timing of these blocks. Here we discuss the use of various neurolytic blocks for cancer pain and detail some of the recent literature and our experience.


Cancer pain Neurolysis 



Dr. Allen Burton received research funding from Medtronic, Inc, has served as a consultant for Infusion Systems and Stryker, and served as a speaker for Elan. Dr. Dhanalakshmi Koyyalagunta has received research funding from Medtronic, Inc.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Department of Pain MedicineThe University of Texas MD Anderson Cancer CenterHoustonUSA

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