An expansion of Simons’ integrated hypothesis of trigger point formation


Simons’ integrated hypothesis proposed a model of trigger point (TrP) activation to explain known TrP phenomena, particularly endplate noise. We propose an expansion of this hypothesis to account for new experimental data and established muscle pathophysiology.

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Gerwin, R.D., Dommerholt, J. & Shah, J.P. An expansion of Simons’ integrated hypothesis of trigger point formation. Current Science Inc 8, 468–475 (2004).

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  • Trigger Point
  • Eccentric Exercise
  • Eccentric Contraction
  • Myofascial Pain Syndrome
  • Motor Nerve Terminal