Current Pain and Headache Reports

, Volume 8, Issue 6, pp 468–475 | Cite as

An expansion of Simons’ integrated hypothesis of trigger point formation

  • Robert D. Gerwin
  • Jan Dommerholt
  • Jay P. Shah


Simons’ integrated hypothesis proposed a model of trigger point (TrP) activation to explain known TrP phenomena, particularly endplate noise. We propose an expansion of this hypothesis to account for new experimental data and established muscle pathophysiology.


Trigger Point Eccentric Exercise Eccentric Contraction Myofascial Pain Syndrome Motor Nerve Terminal 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Current Science Inc 2004

Authors and Affiliations

  • Robert D. Gerwin
    • 1
  • Jan Dommerholt
  • Jay P. Shah
  1. 1.Johns Hopkins University, Pain and Rehabilitation MedicineBethesdaUSA

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