Abstract
Cluster headache is one of the most excruciating headaches affecting human beings—especially the male sex. Most of the cluster headache cases are of episodic nature, with active cluster periods lasting generally between a few weeks and 2 or 3 months. A still undetermined percentage of patients report nonpainful sensations preceding the onset of the pain attack for a variable period of time. If occurring only a few minutes or a few hours before the onset of pain, such symptoms are called prodromal. When occurring for several days, weeks, or months before the pain, they are termed premonitory symptoms. The author believes that premonitory symptoms have not been properly diagnosed and emphasizes the need to investigate their presence, because by knowing them advances can be made in the understanding of the physiopathology of this particular cephalalgia. Furthermore, it can also allow the physician to be ahead, by giving preventive treatment and stopping or diminishing the intensity and duration of the pain attacks.
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References and Recommended Reading
May A, Bahra A, Buchel C, et al.: Hypothalamic activation in cluster headache attacks. Lancet 1998, 352:275–278.
Kudrow L: Cluster headache. In Migraine. Clinical, Therapeutic, Conceptual and Research Aspects. Edited by Blau JN. London: Chapman and Hall Medical; 1987:113–133.
Mathew NT: Cluster headache. Neurology 1992, 42(suppl 2):22–31.
Headache Classification Committee of the International Headache Society: Classification and diagnostic criteria for headache disorders, cranial neuralgias and facial pain. Cephalalgia 1988, 8(suppl 7):1–96.
Noronha A, Appelbaum J: Symptomatic cluster. Neurology 1993, 43:1270.
Blau JN, Engel HO: Premonitory and prodromal symptoms in cluster headache. Cephalalgia 1998, 18:91–93. s paper provides an excellent summary of the prodromal and premonitory symptoms in 150 patients with cluster headache
Wheeler SD: Significance of migrainous features in cluster headache: divalproex responsiveness. Headache 1998, 38:547–551.
Raimondi E: Cluster headache. Premonitory symptoms. Headache 1999, 39:565–566. s paper reports the history of four patients who consulted for cluster headache who had premonitory symptoms.
Wolff HG: Headache and Other Head Pain. New York: Oxford Press;1963.
Blau JN, ed: Adult migraine: the patient observed. In Migraine. Clinical, Therapeutic, Conceptual and Research Aspects. London: Chapman and Hall Medical; 1987:3–30.
Jorge RE, Leston JE, Arndt S, et al.: Cluster headache. Association with anxiety disorders and memory deficits. Neurology 1999, 53:543–547. s is a well-conducted clinical study to explore psychiatric comorbidity and memory and executive functions among patients with cluster headache during the course of an acute episode
Martelletti P, Giacovazzo M: Putative neuroimmunological mechanisms in cluster headache: an integrated hypothesis. Headache 1996, 36:312–315.
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Raimondi, E. Premonitory symptoms in cluster headache. Current Science Inc 5, 55–59 (2001). https://doi.org/10.1007/s11916-001-0010-5
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DOI: https://doi.org/10.1007/s11916-001-0010-5