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Recent Advances in the Role of Diet in Bone and Mineral Disorders in Chronic Kidney Disease

  • Kidney and Bone (IB Salusky and T Nickolas, Section Editors)
  • Published:
Current Osteoporosis Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

Chronic kidney disease mineral and bone disease (CKD-MBD) is a common complication of kidney disease and is strongly influenced by diet. The purpose of this manuscript is to review recent advances in the role of diet in CKD-MBD over the last 5 years.

Recent Findings

Many of the recent studies examining the role of diet in CKD-MBD have focused on the adverse effects of high phosphorus consumption on bone health and metabolism. In general, the studies have shown that high phosphorus consumption worsens markers of bone and mineral metabolism but that eating a diet with a calcium to phosphorus ratio closer to 1:1 can attenuate some of these effects. Recent studies also showed that dietary counseling is efficacious for improving markers of CKD-MBD.

Summary

High consumption of phosphorus aggravates CKD-MBD. Dietary counseling may ameliorate these effects, for example, by consuming diets with higher calcium to phosphorus ratios.

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Funding

Dr. Gutiérrez was supported by grant K24DK116180 from the National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health.

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Authors and Affiliations

  1. Division of Nephrology, Department of Medicine, School of Medicine, University of Alabama at Birmingham, THT 647, 1720 2nd AVE S, Birmingham, AL, 35294-0006, USA

    Orlando M. Gutiérrez

  2. Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, THT 647, 1720 2nd AVE S, Birmingham, AL, 35294-0006, USA

    Orlando M. Gutiérrez

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Correspondence to Orlando M. Gutiérrez.

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Conflict of Interest

Dr. Gutierrez reports receiving grant support and honoraria from Amgen and Akebia; grant support from GSK; honoraria from AstraZeneca, Ardelyx, and Reata; and serving on the Data Monitoring Committee for QED Therapeutics.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Kidney and Bone

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Gutiérrez, O.M. Recent Advances in the Role of Diet in Bone and Mineral Disorders in Chronic Kidney Disease. Curr Osteoporos Rep 19, 574–579 (2021). https://doi.org/10.1007/s11914-021-00710-x

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