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Celiac Disease—Musculoskeletal Manifestations and Mechanisms in Children to Adults

  • Bone and Joint Pain (T King and S Amin, Section Editors)
  • Published:
Current Osteoporosis Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

We aim to review the current literature on the association of musculoskeletal disorders and celiac disease that is a common disorder, affecting about 1% of the population. Extra-intestinal symptoms and presentations predominate.

Recent Findings

While the literature supports an association with reduced bone mineral density and increased fracture risk and celiac disease, there is little evidence supporting associations with other rheumatological conditions. Patients frequently report musculoskeletal symptoms; however, studies of specific disease entities suffer from a lack of standardization of testing for celiac disease and a lack of control groups.

Summary

Well-controlled, preferably population-based studies are required to further explore a relationship between celiac disease and musculoskeletal disorders.

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  1. Celiac Disease Center, Columbia University Medical Center, 180 Fort Washington Ave, New York, NY, 10032, USA

    Haley M. Zylberberg, Benjamin Lebwohl & Peter H.R. Green

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Peter Green reports personal fees from ImmusanT, Celimmune, and J&J for serving on the medical advisory boards, outside the submitted work.

Haley M Zylberberg and Benjamin Lebwohl declare no conflict of interest.

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This article is part of the Topical Collection on Bone and Joint Pain

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Zylberberg, H.M., Lebwohl, B. & Green, P.H. Celiac Disease—Musculoskeletal Manifestations and Mechanisms in Children to Adults. Curr Osteoporos Rep 16, 754–762 (2018). https://doi.org/10.1007/s11914-018-0488-y

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