Dietary Approaches for Bone Health: Lessons from the Framingham Osteoporosis Study
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Osteoporosis is characterized by systemic impairment of bone mass, strength, and microarchitecture, resulting in increased risk for fragility fracture, disability, loss of independence, and even death. Adequate nutrition is important in achieving and maintaining optimal bone mass, as well as preventing this debilitating disease. It is widely accepted that adequate calcium and vitamin D intake are necessary for good bone health; however, nutritional benefits to bone go beyond these two nutrients. This review article will provide updated information on all nutrients and foods now understood to alter bone health. Specifically, this paper will focus on related research from the Framingham Osteoporosis Study, an ancillary study of the Framingham Heart Study, with data on more than 5000 adult men and women.
KeywordsNutrition Diet Bone mineral density Fracture
DP Kiel received grant (R01 AR 41398) from National Institute for Arthritis Musculoskeletal and Skin Diseases, during the conduct of the study.
Compliance with Ethics Guidelines
Conflict of Interest
S Sahni has received research grants from General Mills Bell Institute of Health and Nutrition. KM Mangano declares no conflicts of interest. RR McLean has received research grants from General Mills Bell Institute of Health and Nutrition. MT Hannan has received research grants from General Mills Bell Institute of Health and Nutrition. DP Kiel declares no conflicts of interest.
Human and Animal Rights and Informed Consent
All studies by S Sahni, KM Mangano, RR McLean, MT Hannan, and DP Kiel involving animal and/or human subjects were performed after approval by the appropriate institutional review boards. When required, written informed consent was obtained from all participants.
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