Qigong or Tai Chi in Cancer Care: an Updated Systematic Review and Meta-analysis

Abstract

Purpose of Review

Qigong and Tai Chi are two increasingly popular mind-body interventions with the potential to address the multifaceted needs of cancer survivors. The aim of this updated review and meta-analysis was to quantitatively evaluate the treatment effects of Qigong/Tai Chi on cancer survivors since 2014.

Recent Findings

There were statistically significant and clinically meaningful effects in favor of Qigong/Tai Chi interventions for symptoms of fatigue and sleep quality. There were positive trends, but not statistically significant effects, observed for anxiety, stress, depressive symptoms, and overall quality of life (QOL). Cancer-related cognitive impairment is a common complaint among cancer survivors that has received increasing attention in this area in recent years.

Summary

Qigong/Tai Chi in cancer care shows great promise with short-term effects in treating many cancer-related symptoms. Further methodologically sound trials with longer follow-up periods and more active control conditions are required, before definitive conclusions can be recommended for cancer patients.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. 1.

    Siegel RL, Miller KD, Jemal A. Cancer statistics, 2018. CA Cancer J Clin. 2018;68:7–30.

    Article  Google Scholar 

  2. 2.

    Wefel JS, Kesler SR, Noll KR, Schagen SB. Clinical characteristics, pathophysiology, and management of noncentral nervous system cancer-related cognitive impairment in adults. CA Cancer J Clin. 2015;65:123–38.

    Article  Google Scholar 

  3. 3.

    • Wayne PM, Lee MS, Novakowski J, Osypiuk K, Ligibel J, Carlson LE, et al. Tai chi and qigong for cancer-related symptoms and quality of life: a systematic review and meta-analysis. J Cancer Surviv. 2018;12(2):256–67 This review is of importance as it provides recent summary of the benefits of tai chi and qigong in cancer.

    Article  Google Scholar 

  4. 4.

    • Carlson LE, Zelinski E, Toivonen K, Flynn M, Qureshi M, Piedalue KA, et al. Mind-body therapies in cancer: what is the latest evidence? Curr Oncol Rep. 2017;19(10):67 This review is of special importance as it provides recent and comprehensive summary of the benefits of all mind-body therapies in cancer care.

    Article  Google Scholar 

  5. 5.

    • Zeng Y, Luo T, Xie H, Huang M, Cheng AS. Health benefits of qigong or tai chi for cancer patients: a systematic review and meta-analyses. Complement Ther Med. 2014;22(1):173–86 This study is of special importance as this updated review is based on this review, which provides its depth and breadth of outcomes associated with the health benefits of Qigong/Tai Chi in cancer care.

    Article  Google Scholar 

  6. 6.

    • Greenlee H, DuPont-Reyes MJ, Balneaves LG, Carlson LE, Cohen MR, Deng G, et al. Clinical practice guidelines on the evidence-based use of integrative therapies during and after breast cancer treatment. CA Cancer J Clin. 2017;67(3):194–232 This review is of importance because it provides a comprehensive resource of integrative therapies in cancer care.

    Article  Google Scholar 

  7. 7.

    Jahnke R, Larkey L, Rogers C, Etnier J, Lin F. A comprehensive review of health benefits of qigong and tai chi. Am J Health Promot. 2010;24(6):e25.

    Article  Google Scholar 

  8. 8.

    Campo RA, Agarwal N, LaStayo PC, O'Connor K, Pappas L, Boucher KM, et al. Levels of fatigue and distress in senior prostate cancer survivors enrolled in a 12-week randomized controlled trial of qigong. J Cancer Surviv. 2014;8(1):60–9.

    Article  Google Scholar 

  9. 9.

    Chuang TY, Yeh ML, Chung YC. A nurse facilitated mind-body interactive exercise (Chan-Chuang Qigong) improves the health status of non-Hodgkin lymphoma patients receiving chemotherapy: randomised controlled trial. Int J Nurs Stud. 2017;69:25–33.

    Article  Google Scholar 

  10. 10.

    Loh SY, Lee SY, Murray L. The Kuala Lumpur qigong trial for women in the cancer survivorship phase-efficacy of a three-arm RCT to improve QOL. Asian Pac J Cancer Prev. 2014;15(19):8127–34.

    Article  Google Scholar 

  11. 11.

    Myers JS, Mitchell M, Krigel S, Steinhoff A, Boyce-White A, Van Goethem K, et al. Qigong intervention for breast cancer survivors with complaints of decreased cognitive function. Support Care Cancer. 2018. https://doi.org/10.1007/s00520-018-4430-8.

  12. 12.

    Oh B, Butow P, Boyle F, Costa DSJ, Pavlakis N, et al. Effects of qigong on quality of life, fatigue, stress, neuropathy, and sexual function in women with metastatic breast cancer: a feasibility study. Int J Phys Med Rehabil. 2014;2:217.

    Google Scholar 

  13. 13.

    Vanderbyl BL, MayerMJ NC, Tran AT, Windholz T, Swanson T, et al. A comparison of the effects of medical qigong and standard exercise therapy on symptoms and quality of life in patients with advanced cancer. Support Care Cancer. 2017;25(6):1749–58.

    CAS  Article  Google Scholar 

  14. 14.

    Yeh ML, Chung YC. A randomized controlled trial of qigong on fatigue and sleep quality for non-Hodgkin's lymphoma patients undergoing chemotherapy. Eur J Oncol Nurs. 2016;23:81–6.

    Article  Google Scholar 

  15. 15.

    Larkey LK, Roe DJ, Weihs KL, Jahnke R, Lopez AM, Rogers CE, et al. Randomized controlled trial of qigong/tai chi easy on cancer-related fatigue in breast cancer survivors. Ann Behav Med. 2015;49(2):165–76.

    Article  Google Scholar 

  16. 16.

    Larkey LK, Roe DJ, Smith L, Millstine D. Exploratory outcome assessment of qigong/tai chi easy on breast cancer survivors. Complement Ther Med. 2016;29:196–203.

    Article  Google Scholar 

  17. 17.

    McQuade JL, Prinsloo S, Chang DZ, Spelman A, Wei Q, Basen-Engquist K, et al. Qigong/tai chi for sleep and fatigue in prostate cancer patients undergoing radiotherapy: a randomized controlled trial. Psychooncology. 2017;26(11):1936–43.

    Article  Google Scholar 

  18. 18.

    Thongteratham N, Kanaungnit P, Olson K, Adune R, Dechavudh N, Doungrut W. Effectiveness of tai chi qi qong program for Thai women with breast cancer: a randomized control trial. Pac Rim Int J Nurs Res. 2015;19:280–94.

    Google Scholar 

  19. 19.

    Zhang LL, Wang SZ, Chen HL, Yuan AZ. Tai chi exercise for cancer-related fatigue in patients with lung cancer undergoing chemotherapy: a randomized controlled trial. J Pain Symptom Manag. 2016;51(3):504–11.

    Article  Google Scholar 

  20. 20.

    Rosenthal DS, Doherty-Gilman AM. Integrative medicine and cancer care. Virtual Mentor. 2011;13:379–83.

    Article  Google Scholar 

  21. 21.

    • Klein P, Qigong in cancer care: theory, evidence-base, and practice, Medicines (Basel) 2017; 4(1). This study is noteworthy because it provides theory and evidence-base of how Qigong works.

  22. 22.

    Adler R, Felten DL, Cohen N. Psychoneuroimmunology. 4th ed. San Diego: Academic Press; 2007.

    Google Scholar 

  23. 23.

    Benson H. The relaxation response: updated and expanded. New York: Harper Collins; 2008.

    Google Scholar 

  24. 24.

    Grolleau-Julius A, Ray D, Yung RL. The role of epigenetics in aging and autoimmunity. Clin Rev Allergy Immunol. 2010;39:42–50.

    CAS  Article  Google Scholar 

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Correspondence to Yingchun Zeng.

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Yingchun Zeng, Xiaohua Xie, and Andy S.K. Cheng declare that they have no conflict of interest.

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Zeng, Y., Xie, X. & Cheng, A.S.K. Qigong or Tai Chi in Cancer Care: an Updated Systematic Review and Meta-analysis. Curr Oncol Rep 21, 48 (2019). https://doi.org/10.1007/s11912-019-0786-2

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Keywords

  • Integrative oncology
  • Qigong
  • Tai Chi
  • Fatigue
  • Sleep
  • Anxiety
  • Stress
  • Depression
  • Cognitive function
  • Quality of life (QOL)