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B Vitamin Complex and Chemotherapy-Induced Peripheral Neuropathy

  • Integrative Care (C Lammersfeld, Section Editor)
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Abstract

Purpose of Review

The purpose of this mini review is to evaluate the literature on B vitamins and chemotherapy-induced peripheral neuropathy.

Recent Findings

One hundred and five journal articles were evaluated and nine manuscripts were included. There was one in vitro, one was an animal and seven were human studies. The in vitro study was a safety study on vitamin B6 and oxaliplatin which was not directly related to CIPN. The animal study evaluated vitamin B3 on paclitaxel administration with positive results. The human studies varied using a vitamin B complex, vitamin B12 only and vitamin B6.

Summary

Chemotherapy-induced peripheral neuropathy (CIPN) continues to plague patients and the medical fraternity. Currently, there are still no conclusive protective or treatment options. B vitamins have been found to play a role in CIPN prevention, but further studies are required to ascertain possible protection and treatment options.

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References

Papers of particular interest, published recently, have been highlighted as: •• Of major importance

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Authors and Affiliations

  1. Office of Research, Endeavour College of Natural Health, Brisbane, 4006, Australia

    Janet Schloss

  2. Medical Oncology Group of Australia, Clinical Oncology Society of Australia, Queensland Clinical Oncology Group, Brisbane, 4000, Australia

    Maree Colosimo

Authors
  1. Janet Schloss
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  2. Maree Colosimo
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Correspondence to Janet Schloss.

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Conflict of Interest

Janet Schloss and Maree Colosimo declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Integrative Care

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Schloss, J., Colosimo, M. B Vitamin Complex and Chemotherapy-Induced Peripheral Neuropathy. Curr Oncol Rep 19, 76 (2017). https://doi.org/10.1007/s11912-017-0636-z

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  • DOI: https://doi.org/10.1007/s11912-017-0636-z

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