Does tamoxifen improve the outcome of patients who have undergone lumpectomy and radiation for ductal carcinoma in situ?

Conclusions

In women with ductal carcinoma in situ, in a group including those whose resected sample margins were involved with tumor, the addition of tamoxifen to a treatment regimen of lumpectomy and radiotherapy was effective in preventing cancer in the ipsilateral and contralateral breast at 5 years without affecting survival.