Current Neurology and Neuroscience Reports

, Volume 9, Issue 4, pp 313–318 | Cite as

Alternative approaches to epilepsy treatment

  • Caitlin McElroy-Cox


Complementary and alternative medicine (CAM) is a diverse group of health care practices and products that fall outside the realm of traditional Western medical theory and practice and that are used to complement or replace conventional medical therapies. The use of CAM has increased over the past two decades, and surveys have shown that up to 44% of patients with epilepsy are using some form of CAM treatment. This article reviews the CAM modalities of meditation, yoga, relaxation techniques, biofeedback, nutritional and herbal supplements, dietary measures, chiropractic care, acupuncture, Reiki, and homeopathy and what is known about their potential efficacy in patients with epilepsy.


Seizure Frequency Ketogenic Diet Herbal Remedy Refractory Epilepsy Intractable Epilepsy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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References and Recommended Reading

  1. 1.
    National Center for Complementary and Alternative Medicine: What is CAM? Available at Accessed May 21, 2009.
  2. 2.
    Eisenberg DM, Davis RB, Ettner SL, et al.: Trends in alternative medicine use in the United States, 1990–1997. JAMA 1998, 280:1569–1575.PubMedCrossRefGoogle Scholar
  3. 3.
    Tindle HA, Davis RB, Phillips RS, et al.: Trends in use of complementary and alternative medicine by US adults: 1997–2002. Altern Ther Health Med 2005, 11:42–49.PubMedGoogle Scholar
  4. 4.
    National Center for Complementary and Alternative Medicine: The Use of Complementary and Alternative Medicine in the United States. Available at Accessed May 21, 2009.
  5. 5.
    Kwan P, Brodie MJ: Early identification of refractory epilepsy. N Engl J Med 2000, 342:314–319.PubMedCrossRefGoogle Scholar
  6. 6.
    Peebles CT, McAuley JW, Roach J, et al.: Alternative medicine use by patients with epilepsy. Epilepsy Behav 2000, 1:74–77.PubMedCrossRefGoogle Scholar
  7. 7.
    Sirven JI, Drazkowski JF, Zimmerman RS, et al.: Complementary/alternative medicine for epilepsy in Arizona. Neurology 2003, 61:576–577.PubMedGoogle Scholar
  8. 8.
    Liow K, Ablah E, Nguyen JC, et al.: Pattern and frequency of use of complementary and alternative medicine among patients with epilepsy in the Midwestern United States. Epilepsy Behav 2007, 10:576–582.PubMedCrossRefGoogle Scholar
  9. 9.
    National Center for Complementary and Alternative Medicine: Mind-Body Medicine: An Overview. Available at Accessed May 21, 2009.
  10. 10.
    Arias AJ, Steinberg K, Banga A, et al.: Systematic review of the efficacy of meditation techniques as treatments for medical illness. J Altern Complement Med 2006, 12:817–832.PubMedCrossRefGoogle Scholar
  11. 11.
    Panjwani U, Selvamurthy W, Singh SH, et al.: Effect of Sahaja yoga practice on seizure control & EEG changes in patients with epilepsy. Indian J Med Res 1996, 103:165–172.PubMedGoogle Scholar
  12. 12.
    Panjwani U, Gupta HL, Singh SH, et al.: Effect of Sahaja yoga practice on stress management in patients with epilepsy. Indian J Physiol Pharmacol 1995, 39:111–116.PubMedGoogle Scholar
  13. 13.
    Deepak KK, Manchanda SK, Maheshwari MC: Meditation improves clinicoelectroencephalographic measures in drug-resistant epileptics. Biofeedback Self Regul 1994, 19:25–40.PubMedCrossRefGoogle Scholar
  14. 14.
    Sathyaprabha TN, Satishchandra P, Pradhan C, et al.: Modulation of cardiac autonomic balance with adjuvant yoga therapy in patients with refractory epilepsy. Epilepsy Behav 2008, 12:245–252.PubMedCrossRefGoogle Scholar
  15. 15.
    Dahl JA, Melin L, Lund L: Effects of a contingent relaxation treatment program on adults with refractory epileptic seizures. Epilepsia 1987, 28:125–132.PubMedCrossRefGoogle Scholar
  16. 16.
    Puskarich CA, Whitman S, Dell J, et al.: Controlled examination of effects of progressive relaxation training on seizure reduction. Epilepsia 1992, 33:675–680.PubMedCrossRefGoogle Scholar
  17. 17.
    Nagai Y, Goldstein LH, Fenwick PB, Trimble MR: Clinical efficacy of galvanic skin response biofeedback training in reducing seizures in adult epilepsy: a preliminary randomized controlled study. Epilepsy Behav 2004, 5:216–223.PubMedCrossRefGoogle Scholar
  18. 18.
    Lantz D, Sterman MB: Neuropsychological assessment of subjects with uncontrolled epilepsy: effects of EEG feedback training. Epilepsia 1988, 29:163–171.PubMedCrossRefGoogle Scholar
  19. 19.
    Monderer RS, Harrison DM, Haut SR: Neurofeedback and epilepsy. Epilepsy Behav 2002, 3:214–218.PubMedCrossRefGoogle Scholar
  20. 20.
    Egner T, Sterman MB: Neurofeedback treatment of epilepsy: from basic rational to practical application. Expert Rev Neurother 2006, 6:247–257.PubMedCrossRefGoogle Scholar
  21. 21.
    Yardi N: Yoga for control of epilepsy. Seizure 2001, 10:7–12.PubMedCrossRefGoogle Scholar
  22. 22.
    Kaufman DW, Kelly JP, Rosenberg L, et al.: Recent patterns of medication use in the ambulatory adult population of the United States: the Slone survey. JAMA 2002, 287:337–344.PubMedCrossRefGoogle Scholar
  23. 23.
    Singer N: FDA finds ‘natural’ diet pills laced with drugs. New York Times. February 9, 2009. Available at Accessed May 21, 2009.
  24. 24.
    Tyagi A, Delanty N: Herbal remedies, dietary supplements, and seizures. Epilepsia 2003, 44:228–235.PubMedCrossRefGoogle Scholar
  25. 25.
    Samuels N, Finkelstein Y, Singer SR, et al.: Herbal medicine and epilepsy: proconvulsant effects and interactions with antiepileptic drugs. Epilepsia 2008, 49:373–380.PubMedCrossRefGoogle Scholar
  26. 26.
    Bromfield E, Dworetzky B, Hurwitz S, et al.: A randomized trial of polyunsaturated fatty acids for refractory epilepsy. Epilepsy Behav 2008, 12:187–190.PubMedCrossRefGoogle Scholar
  27. 27.
    Ferrari D, Cysneiros RM, Scorza CA, et al.: Neuroprotective activity of omega-3 fatty acids against epilepsy-induced hippocampal damage: quantification with immunohistochemical for calcium-binding proteins. Epilepsy Behav 2008, 13:36–42.PubMedCrossRefGoogle Scholar
  28. 28.
    Yuen AW, Sander JW, Fluegel D, et al.: Omega-3 fatty acid supplementation in patients with chronic epilepsy: a randomized trial. Epilepsy Behav 2005, 7:253–258.PubMedCrossRefGoogle Scholar
  29. 29.
    Scorza FA, Cysneiros RM, Arida RM, et al.: The other side of the coin: beneficiary effect of omega-3 fatty acids in sudden unexpected death in epilepsy. Epilepsy Behav 2008, 13:279–283.PubMedCrossRefGoogle Scholar
  30. 30.
    Neal EG, Chaffe H, Schwartz RH, et al.: The ketogenic diet for the treatment of childhood epilepsy: a randomized controlled trial. Lancet Neurol 2008, 7:500–506.PubMedCrossRefGoogle Scholar
  31. 31.
    Kossoff EH, Dorward JL: The modified Atkins diet. Epilepsia 2008, 49(Suppl 8):37–41.PubMedCrossRefGoogle Scholar
  32. 32.
    Weber S, Molgaard C, Taudorf K, et al.: Modified Atkins diet to children and adolescents with medical intractable epilepsy. Seizure 2009, 18:237–240.PubMedCrossRefGoogle Scholar
  33. 33.
    Ojemann LM, Nelson WL, Shin DS, et al.: Tian ma, an ancient Chinese herb, offers new options for the treatment of epilepsy and other conditions. Epilepsy Behav 2006, 8:376–383.PubMedCrossRefGoogle Scholar
  34. 34.
    Hijikata Y, Yasuhara A, Yoshida Y, et al.: Traditional Chinese medicine treatment of epilepsy. J Altern Complement Med 2006, 12:673–677.PubMedCrossRefGoogle Scholar
  35. 35.
    Pistolese RA: Epilepsy and seizure disorders: a review of literature relative to chiropractic care of children. J Manipulative Physiol Ther 2001, 24:199–205.PubMedGoogle Scholar
  36. 36.
    Elster EL: Treatment of bipolar, seizure, and sleep disorders and migraine headaches utilizing a chiropractic technique. J Manipulative Physiol Ther 2004, 27:E5.PubMedCrossRefGoogle Scholar
  37. 37.
    Yongxia R: Acupuncture treatment of Jacksonian epilepsy—a report of 98 cases. J Tradit Chin Med 2006, 26:177–178.PubMedGoogle Scholar
  38. 38.
    Kim ST, Jeon S, Park HJ, et al.: Acupuncture inhibits kainic acid-induced hippocampal cell death in mice. J Physiol Sci 2008, 58:31–38.PubMedCrossRefGoogle Scholar
  39. 39.
    Cheuk DK, Wong V: Acupuncture for epilepsy. Cochrane Database Syst Rev 2008 (4):CD005062Google Scholar
  40. 40.
    Kloster R, Larsson PG, Lossius R, et al.: The effect of acupuncture in chronic intractable epilepsy. Seizure 1999, 8:170–174.PubMedCrossRefGoogle Scholar
  41. 41.
    A R Kumar, Kurup PA: Changes in the isoprenoid pathway with transcendental meditation and Reiki healing practices in seizure disorder. Neurol India 2003, 51:211–214.Google Scholar
  42. 42.
    Ricotti V, Delanty N: Use of complementary and alternative medicine in epilepsy. Curr Neurol Neurosci Rep 2006, 6:347–353.PubMedCrossRefGoogle Scholar
  43. 43.
    Schacter SC: Complementary and alternative medical therapies. Curr Opin Neurol 2008, 21:184–189.CrossRefGoogle Scholar

Copyright information

© Current Medicine Group, LLC 2009

Authors and Affiliations

  1. 1.Columbia Comprehensive Epilepsy CenterColumbia University, Neurologic InstituteNew YorkUSA

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