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The Epidemiology and Prevention of Candida auris

Current Infectious Disease Reports volume 21, Article number: 19 (2019) Cite this article

Abstract

Purpose of Review

Candida auris has recently emerged as a pathogen with the potential for nosocomial transmission and outbreaks. The aim of this review is to summarize the global dissemination of this pathogen, characterize patient and facility characteristics associated with infection and outbreaks, and outline evidence to support interventions to prevent of transmission in the healthcare setting.

Recent Findings

C. auris has emerged separately in four clades, with international spread within a decade of its first identification and report. Acquisition and infection have predominantly been identified as healthcare-associated events. The presence of invasive devices, intensive care, and broad-spectrum antibiotic and antifungal use may be important risk factors for the development of infection due to C. auris. Nosocomial transmission is likely associated with colonization density and suboptimal infection prevention practices. The optimal strategy for reducing transmission from the environment requires further study.

Summary

Candida auris is a recently emerging fungal pathogen that may cause nosocomial infections and outbreaks. Based on observed transmission patterns and interventions, key prevention measures outlined in the review include case finding and surveillance, hand hygiene, and environmental disinfection.

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Notes

  1. In this review, “carriage” refers to studies not differentiating between colonization and infection.

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Affiliations

  1. Department of Infection Prevention and Control, University of Pittsburgh Medical Center, 3601 5th Avenue, Falk Medical Building, Suite 150, Pittsburgh, PA, 15213, USA

    Graham M. Snyder

  2. Division of Infection Control/Hospital Epidemiology, Silverman Institute of Health Care Quality and Safety, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Mailstop SL-435, Boston, MA, 02215, USA

    Sharon B. Wright

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  1. Graham M. Snyder
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Snyder, G.M., Wright, S.B. The Epidemiology and Prevention of Candida auris. Curr Infect Dis Rep 21, 19 (2019). https://doi.org/10.1007/s11908-019-0675-8

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Keywords

  • Infection prevention and control
  • Transmission
  • Outbreak
  • Emerging pathogen