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Septic Arthritis in the Native Joint

Current Infectious Disease Reports volume 14, pages 558–565 (2012)Cite this article

Abstract

Septic arthritis of the native joint is an uncommon infection but, when present, creates a significant risk for functional impairment of the affected joint or, in severe cases, mortality. Knowledge of the most common pathogens, as well as appropriate diagnostics, can facilitate earlier diagnosis and treatment, which, ideally, leads to improved long-term outcomes. In this article, we discuss recent microbiologic trends and diagnostic tests, with an update on use of molecular testing. Empiric antibiotic regimens for native joint septic arthritis are reviewed, as well as potential new therapies on the horizon.

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Author information

Affiliations

  1. Division of Infectious Disease, University of Wisconsin School of Medicine and Public Health, 1685 Highland Avenue, Madison, WI, 53705, USA

    Meghan B. Brennan

  2. Sanford Health Infectious Disease, 1205 South Grange Avenue, Suite 401, Sioux Falls, SD, 57105, USA

    Jennifer L. Hsu

  3. Department of Internal Medicine, Sanford School of Medicine of the University of South Dakota, 1400 West 22nd Street, Sioux Falls, SD, 57105, USA

    Jennifer L. Hsu

Authors
  1. Meghan B. Brennan
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  2. Jennifer L. Hsu
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Correspondence to Jennifer L. Hsu.

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Brennan, M.B., Hsu, J.L. Septic Arthritis in the Native Joint. Curr Infect Dis Rep 14, 558–565 (2012). https://doi.org/10.1007/s11908-012-0285-1

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  • DOI: https://doi.org/10.1007/s11908-012-0285-1

Keywords

  • Septic arthritis
  • Infectious arthritis
  • Osteoarticular infection
  • Hot swollen joint
  • Staphylococcus aureus
  • Arthrocentesis
  • Synovial fluid
  • White blood cell count
  • Culture
  • Polymerase chain reaction
  • Antibiotics
  • Joint drainage
  • Dexamethasone
  • Bisphosphonates