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Current Infectious Disease Reports

, Volume 12, Issue 3, pp 165–173 | Cite as

Drug-Resistant Malaria: The Era of ACT

  • Jessica T. Lin
  • Jonathan J. Juliano
  • Chansuda Wongsrichanalai
Article

Abstract

As drug-resistant falciparum malaria has continued to evolve and spread worldwide, artemisinin-based combination therapies (ACT) have become the centerpiece of global malaria control over the past decade. This review discusses how advances in antimalarial drug resistance monitoring and rational use of the array of ACTs now available can maximize the impact of this highly efficacious therapy, even as resistance to artemisinins is emerging in Southeast Asia.

Keywords

Drug-resistant malaria Artemisinin-based combination therapy ACT Plasmodium falciparum Antimalarial resistance 

Notes

Disclosure

No potential conflict of interest relevant to this article was reported.

References

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Jessica T. Lin
    • 1
  • Jonathan J. Juliano
    • 2
  • Chansuda Wongsrichanalai
    • 3
  1. 1.Division of Infectious DiseasesUniversity of North Carolina School of MedicineChapel HillUSA
  2. 2.Center for Infectious DiseasesUniversity of North CarolinaChapel HillUSA
  3. 3.BangkokThailand

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