Conclusions
After considering the evidence available and the relative merits as well as problems with the AHA recommendations, we believe that the recommendations for prophylaxis should be eliminated or changed to optional for all conditions other than previous valvular surgery, previous endocarditis, and congenital cyanotic heart disease.
Similar content being viewed by others
References
Dajani AS, Taubert KA, Wilson W, et al.: Prevention of bacterial endocarditis: recommendations by the American Heart Association. JAMA 1997, 227:1794–1801.
Strom BL, Abrutyn E, Berlin JA, et al.: Dental and cardiac risk factors for infective endocarditis. Ann Intern Med 1998, 129:761–769.
Hall G, Heimdahl A, Nord CE: Bacteremia after oral surgery and antibiotic prophylaxis for endocarditis. Clin Infect Dis 1999, 29:1–10.
Berney P, Francioli P: Successful prophylaxis of experimental streptococcal endocarditis with single-dose amoxicillin administered after bacterial challenge. J Infect Dis 1990, 161:281–285.
Steckelberg JM, Wilson WR: Risk factors for infective endocarditis. Infect Dis Clin North Am 1993, 7:9–19.
Freed LA, Levy D, Levine RA, et al.: Prevalence and clinical outcome of mitral-valve prolapse. N Engl J Med 1999, 341:1–7.
Vlessis AA, Hovaguimian H, Jaggers J, et al.: Infective endocarditis: ten year review of medical and surgical therapy. Ann Thorac Surg 1996, 61:1217–1222.
Sullivan NM, Sutter VL, Mims MM, et al.: Clinical aspects of bacteremia after manipulation of the genitourinary tract. J Infect Dis 1973, 127:49–55.
Everett ED, Hirschmann JV: Transient bacteremia and endocarditis prophylaxis. A review. Medicine 1977, 56:61–77.
Lacassin F, Hoen B, Leport C, et al.: Procedures associated with infective endocarditis in adults. A case control study. Eur Heart J 1995, 16:1968–1974.
Strom BL, Abrutyn E, Berlin JA, et al.: Risk factors for infective endocarditis: oral hygiene and nondental exposures. Circulation 2000, 102:2842–2848.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kaye, D., Zuckerman, J.M. Antibiotic prophylaxis of endocarditis: What is accomplished and at what cost?. Curr Infect Dis Rep 5, 1–3 (2003). https://doi.org/10.1007/s11908-003-0056-0
Issue Date:
DOI: https://doi.org/10.1007/s11908-003-0056-0