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Effect of Egg Consumption on Blood Pressure: a Systematic Review and Meta-analysis of Randomized Clinical Trials

  • Nutrition and Hypertension (T Mori, Section Editor)
  • Published:
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Purpose of Review

We identified and quantified the results of randomized controlled trials (RCTs) that have assessed the impact of egg consumption on blood pressure in adults.

Recent Findings

We conducted a comprehensive search of medical bibliographic databases up to February 2019 for RCTs investigating the effect of egg consumption on blood pressure in adults. Fifteen RCTs were included with a total of 748 participants. Overall, egg consumption had no significant effect on systolic blood pressure (weighted mean difference (WMD) = 0.046 mmHg; 95% CI − 0.792, 0.884) and diastolic blood pressure (WMD = − 0.603 mmHg; 95% CI − 1.521, 0.315). Subgroup analyses had no effect on pooled results and no heterogeneity was found among included studies.


Egg consumption has no significant effects on systolic and diastolic blood pressure in adults. Due to several limitations among existing studies, general conclusions cannot be drawn regarding the beneficial or neutral impact of egg consumption on blood pressure in adults.

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Cardiovascular diseases




Coronary heart disease


Relative risk


Randomized controlled trials


Systolic blood pressure


Diastolic blood pressure


Preferred reporting items for systematic review and meta-analyses


Prospective register of systematic reviews


Weighted mean differences


Coronary artery disease


Ischemic heart disease








Nitric oxide


Angiotensin converting enzyme


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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We thank Iran University of Medical Sciences for providing facilities to search in electronic databases.

Availability of Data and Material

It was registered in the PROSPERO (international prospective register of systematic reviews) database under the number CRD42019127500.


ZSC is currently supported by NIH T32 DK007135-44.

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Authors and Affiliations



RKM screened and selected the trials, extracted the data, and wrote the manuscript. MM screened and selected the trials, extracted the data, and assessed quality of included studies. ZSC reviewed and edited the manuscript. SZS screened the trials. NP screened and selected the trials and assessed quality of included studies. MKS screened the trials. SS conceived the idea, conducted the research, analyzed the data, and performed statistical analysis and had primary responsibility for final content. All authors read and approved the final manuscript.

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Correspondence to Sepideh Soltani.

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Kolahdouz-Mohammadi, R., Malekahmadi, M., Clayton, Z.S. et al. Effect of Egg Consumption on Blood Pressure: a Systematic Review and Meta-analysis of Randomized Clinical Trials. Curr Hypertens Rep 22, 24 (2020).

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