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The Un-Observed Automated Office Blood Pressure Measurement Technique Used in the SPRINT Study Points to a Standard Target Office Systolic Blood Pressure <140 mmHg


The SPRINT study investigators used the un-observed automated office blood pressure measurement technique. When their achieved systolic blood pressure is corrected, target systolic blood pressure for most people remains unchanged: <140mmHg for prevention of cardiovascular diseases and death.

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  1. Ambrosius WT, Sink KM, Foy CG, et al. The design and rationale of a multicenter clinical trial comparing two strategies for control of systolic blood pressure: The Systolic Blood Pressure Intervention Trial (SPRINT). Clinical Trials. 2014;11:532–46.

    Article  PubMed  Google Scholar 

  2. The SPRINT Research Group. A randomized trial of intensive versus standard blood-pressure control. N Engl J Med. 2015;373:2103–16.

    Article  PubMed Central  Google Scholar 

  3. Schiffrin EL, Calhoun DA, Flack JM. SPRINT proves that lower is better for non-diabetic high-risk patients, but at a price. Am J Hypertens. 2016;29:2–4.

    Article  PubMed  Google Scholar 

  4. Myers MG, Godwin M, Daves M, et al. Measurement of blood pressure in the office: recognizing the problem and proposing the solution. Hypertension. 2010;55:195–200.

    CAS  Article  PubMed  Google Scholar 

  5. Drawz PE, Pajewski NM, Bates JT, et al. Effect of intensive versus standard clinic-based hypertension management on ambulatory blood pressure. Results from the SPRINT (systolic blood pressure intervention trial) ambulatory blood pressure study. Hypertension. 2017;69:00–00. doi:10.1161/HYPERTENSIONAHA.116.08076.).

  6. Filipovský J, Seidlerová J, Kratochvíl Z, et al. Automated compared to manual office blood pressure and to home blood pressure in hypertensive patients. Blood Press. 2016;25:228–34.

    Article  PubMed  Google Scholar 

  7. Lund-Johansen P. Hemodynamics in early essential hypertension (table 23, page 43). Acta Medica Scand. 1967;181(Suppl.482):2–101.

    Google Scholar 

  8. Mancia G, Bertinieri G, Grassi G, et al. Effects of blood pressure measurements by the doctor on the patientʼs blood pressure and heart rate. Lancet. 1983;2:695–8.

    CAS  Article  PubMed  Google Scholar 

  9. Mancia G, Parati G, Pomidossi G, et al. Alerting reaction and rise in blood pressure during measurement by physician and nurse. Hypertension. 1987;9:209–15.

    CAS  Article  PubMed  Google Scholar 

  10. Parati G, Pomidossi G, Casadei R, Mancia G. Lack of alerting reactions to intermittent cuff inflations during noninvasive blood pressure monitoring. Hypertension. 1985;7:597–601.

    CAS  Article  PubMed  Google Scholar 

  11. Kjeldsen SE, Lund-Johansen P, Nilsson P, Mancia G. Unattended blood pressure measurements in the systolic blood pressure intervention trial. Implications for entry and achieved blood pressure values compared with other trials. Hypertension. 2016;67:808–12.

    CAS  Article  PubMed  Google Scholar 

  12. Kjeldsen SE, Hedner T, Jamerson K, et al. Hypertension optimal treatment (HOT) study: home blood pressures in treated hypertensive subjects. Hypertension. 1998;31:1014–20.

    CAS  Article  PubMed  Google Scholar 

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Correspondence to Sverre E. Kjeldsen.

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Conflict of Interest

Dr. Kjeldsen has received modest honoraria for consultancy and lecturing from ABDiiBRAHiM, Bayer, Merck, and Takeda. Dr. Mancia declares no conflicts of interest relevant to this manuscript.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Kjeldsen, S.E., Mancia, G. The Un-Observed Automated Office Blood Pressure Measurement Technique Used in the SPRINT Study Points to a Standard Target Office Systolic Blood Pressure <140 mmHg. Curr Hypertens Rep 19, 3 (2017).

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  • Antihypertensive drug-treatment
  • Blood pressure measurement
  • Blood pressure target
  • Hypertension
  • Randomized controlled trial