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Sodium sensitivity, not level of salt intake, predicts salt effects

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References

  1. Taubes G: The (political) science of salt. Science 1998, 281:898–907.

    Article  PubMed  CAS  Google Scholar 

  2. Folkow B: Critical review of studies on salt and hypertension. Clin Exp Hypertens 1992, 14:1–14.

    CAS  Google Scholar 

  3. Intersalt Cooperative Research Group: Intersalt: an international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium excretion. BMJ 1988, 297:319–328.

    Google Scholar 

  4. Muntzel M, Drueke T: A comprehensive review of the salt and blood pressure relationship. Am J Hypertens 1992, 5:1S-42S.

    PubMed  CAS  Google Scholar 

  5. Hollenberg NK, Martinez G, McCullough M, et al.: Aging, acculturation, salt intake, and hypertension in the Kuna of Panama. Hypertension 1997, 29:171–176.

    PubMed  CAS  Google Scholar 

  6. Midgley JP, Matthew AG, Greenwood CMT, et al.: Effect of reduced dietary sodium on blood pressure. A meta-analysis of randomized controlled trials. JAMA 1996, 275:1590–1597.

    Article  PubMed  CAS  Google Scholar 

  7. Kumanyika SK, Hebert PR, Cutler JA, et al.: Feasibility and efficacy of sodium reduction in the Trials of Hypertension Prevention, phase I. Hypertension 1993, 22:502–512.

    PubMed  CAS  Google Scholar 

  8. The Trials of Hypertension Prevention Collaborative Research Group: Effects of weight loss and sodium reduction intervention on blood pressure and hypertension incidence in overweight people with high-normal blood pressure. Arch Intern Med 1997, 157:657–667.

    Article  Google Scholar 

  9. Miller JZ, Weinberger MH, Daugherty SA, et al.: Heterogeneity of blood pressure response to dietary sodium restriction in normotensive adults. J Chron Dis 1987, 40:245–250.

    Article  PubMed  CAS  Google Scholar 

  10. Campese VM: Salt sensitivity of blood pressure in humans. Renal and cardiovascular implications. Hypertension 1994, 23:531–550.

    PubMed  CAS  Google Scholar 

  11. Weinberger MH, Fineberg NS: Sodium and volume sensitivity of blood pressure. Age and pressure change over time. Hypertension 1991, 18:67–71.

    PubMed  CAS  Google Scholar 

  12. Cappuccio FP, Markandu ND, Carney C, et al.: Double-blind randomised trial of modest salt restriction in older people. Lancet 1997, 350:850–854.

    Article  PubMed  CAS  Google Scholar 

  13. Mokdad AH, Serdula MK, Dietz WH, et al.: The spread of the obesity epidemic in the United States. JAMA 1999, 282:1519–1522.

    Article  PubMed  CAS  Google Scholar 

  14. Rocchini AP, Key J, Bondie D, et al.: Theeffect of weight loss on the sensitivity of blood pressure to sodium in obese adolescents. N Engl J Med 1989, 321:580–585.

    Article  PubMed  CAS  Google Scholar 

  15. McCarron DA, Morris CD, Henry HJ, et al.: Blood pressure and nutrient intake in the United States. Science 1984, 224:1392–1398.

    Article  PubMed  CAS  Google Scholar 

  16. Krishna G, Miller E, Kapoor S: Increased blood pressure during potassium depletion in normotensive men. N Engl J Med 1989, 320:1177–1182.

    Article  PubMed  CAS  Google Scholar 

  17. Morris RC Jr, Sebastian A, Forman A, et al.: Normotensive salt sensitivity. Effects of race and dietary potassium. Hypertension 1999, 33:18–23.

    PubMed  CAS  Google Scholar 

  18. Gruchow HW, Sobocinski KA, Barboriak JJ: Calcium intake and the relationship of dietary sodium and potassium to blood pressure. Am J Clin Nutr 1988, 48:1463–1470.

    PubMed  CAS  Google Scholar 

  19. McCarron DA: Role of adequate dietary calcium intake in the prevention and management of salt-sensitive hypertension. Am J Clin Nutr 1997, 65(suppl 2):712–716.

    Google Scholar 

  20. Appel LJ, Moore TJ, Obarzanek E, et al.: A clinical trial of the effects of dietary patterns on blood pressure. N Engl J Med 1997, 336:1117–1124.

    Article  PubMed  CAS  Google Scholar 

  21. Calle EE, Thun MJ, Petrelli JM, et al.: Body-mass index and mortality in a prospective cohort of US adults. N Engl J Med 1999, 341:1097–1105.

    Article  PubMed  CAS  Google Scholar 

  22. Khaw K-T, Barrett-Connor E: Dietary potassium and strokeassociated mortality. A 12-year prospective population study. N Engl J Med 1987, 316:235–240.

    Article  PubMed  CAS  Google Scholar 

  23. Iso H, Stampfer MJ, Manson JE, et al.: Prospective study of calcium, potassium, and magnesium intake and risk of stroke in women. Stroke 1999, 30:1772–1779.

    PubMed  CAS  Google Scholar 

  24. Joshipura KJ, Ascherio A, Manson JE, et al.: Fruit and vegetable intake in relation to risk of ischemic stroke. JAMA 1999, 282:1233–1239.

    Article  PubMed  CAS  Google Scholar 

  25. Tunstall-Pedoe H, Woodward M, Tavendale R, et al.: Comparison of the prediction by 27 different factors of coronary heart disease and death in men and women of the Scottish heart health study: cohort study. BMJ 1997, 315:722–729.

    PubMed  CAS  Google Scholar 

  26. Ford ES: Serum magnesium and ischaemic heart disease: findings from a national sample of US adults. Int J Epidemiol 1999, 28:645–651.

    Article  PubMed  CAS  Google Scholar 

  27. Resnick LM, Gupta RK, DiFabio B, et al.: Intracellular ionic consequences of dietary salt loading in essential hypertension. Relation to blood pressure and effects of calcium channel blockade. J Clin Invest 1994, 94:1269–1276.

    Article  PubMed  CAS  Google Scholar 

  28. Alderman MH, Cohen H, Madhaven S: Dietary sodium intake and mortality: the National Health and Nutrition Examination Survey (NHANES I). Lancet 1998, 351:781–785.

    Article  PubMed  CAS  Google Scholar 

  29. He J, Ogden LG, Vupputuri S, et al.: Dietary sodium intake and subsequent risk of cardiovascular disease in overweight adults. JAMA 1999, 282:2027–2034.

    Article  PubMed  CAS  Google Scholar 

  30. Alderman MH, Madhavan S, Cohen H, et al.: Low urinary sodium is associated with greater risk of myocardial infarction among treated hypertensive men. Hypertension 1995, 25:1144–1152.

    PubMed  CAS  Google Scholar 

  31. de Wardener H, MacGregor GA: Sodium intake and mortality. Lancet 1998, 351:1508.

    Article  PubMed  Google Scholar 

  32. Davey Smith G, Neaton JD, Wentworth D, et al.: Mortality differences between black and white men in the USA: contribution of income and other risk factors among men screened for the MRFIT. Lancet 1998, 351:934–939.

    Google Scholar 

  33. Morimoto A, Uzu T, Fujii T, et al.: Sodium sensitivity and cardiovascular events in patients with essential hypertension. Lancet 1997, 350:1734–1737.

    Article  PubMed  CAS  Google Scholar 

  34. de la Sierra A, Lluch MM, Pare JC, et al.: Increased left ventricular mass in salt-sensitive patients. J Hum Hypertens 1996, 10:795–799.

    PubMed  Google Scholar 

  35. Alaimo K, Briefel RR, Frongillo EA, et al.: Food insufficiency exists in the United States: Results from the Third National Health and Nutrition Examination Survey (NHANES III). Am J Public Health 1998, 88:419–426.

    Article  PubMed  CAS  Google Scholar 

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  1. Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, M5G 1X5, Toronto, Ontario, Canada

    Alexander G. Logan MD

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  1. Alexander G. Logan MD
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Logan, A.G. Sodium sensitivity, not level of salt intake, predicts salt effects. Current Science Inc 2, 115–119 (2000). https://doi.org/10.1007/s11906-000-0068-1

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