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The Role of Nutrition in the Pathogenesis and Treatment of Alcohol-Related Liver Disease

  • Nutrition in Patients with Chronic Liver Disease (E Tapper, Section Editor)
  • Published:
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Abstract

Abstract

Malnutrition is increasingly being recognized as a poor prognostic factor in the realm of chronic liver disease, particularly among those individuals with end-stage liver disease undergoing transplant evaluation.

Purpose of Review

The purpose of this review is to demonstrate how nutrition contributes to disease pathogenesis and whether improvements in nutrition can alter disease pathogenesis.

Recent Findings

Recent findings reveal that the role of nutrition is multifaceted, primarily due to alterations in gut microbiota and cytokine release. Additionally, there is increasing data demonstrating that those with gastric bypass are more susceptible to developing end-stage liver disease with lesser amounts of alcohol use.

Summary

The role of nutrition as relates to liver disease is complex and involves not only global calorie replacement but also management of micronutrient deficiencies. Future research should focus on further tools to assess for malnutrition and prevention of sarcopenia.

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Authors and Affiliations

  1. Division of Gastroenterology and Hepatology, Northwestern Feinberg School of Medicine, 676 N St. Clair, Suite 1900, Chicago, IL, 60611, USA

    Haripriya Maddur

  2. Gastroenterology Research Unit, Division of Gastroenterology and Hepatology and Department of Medicine, Mayo Clinic School of Medicine, 200 First St. SW, Rochester, MN, 55905, USA

    Vijay H. Shah

Authors
  1. Haripriya Maddur
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  2. Vijay H. Shah
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Correspondence to Haripriya Maddur.

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This article is part of the Topical Collection on Nutrition in Patients with Chronic Liver Disease

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Maddur, H., Shah, V.H. The Role of Nutrition in the Pathogenesis and Treatment of Alcohol-Related Liver Disease. Curr Hepatology Rep 19, 7–12 (2020). https://doi.org/10.1007/s11901-020-00504-2

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